Price DL - Search Results

1

Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice.

Savonenko AV, Melnikova T, Laird FM, Stewart KA, Price DL, Wong PC. Savonenko AV, et al. Among authors: price dl. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5585-90. doi: 10.1073/pnas.0710373105. Epub 2008 Apr 2. Proc Natl Acad Sci U S A. 2008. PMID: 18385378 Free PMC article.

2

BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.

Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, Wen H, Chiang HC, Xu G, Koliatsos VE, Borchelt DR, Price DL, Lee HK, Wong PC. Laird FM, et al. Among authors: price dl. J Neurosci. 2005 Dec 14;25(50):11693-709. doi: 10.1523/JNEUROSCI.2766-05.2005. J Neurosci. 2005. PMID: 16354928 Free PMC article.

3

Modeling an anti-amyloid combination therapy for Alzheimer's disease.

Chow VW, Savonenko AV, Melnikova T, Kim H, Price DL, Li T, Wong PC. Chow VW, et al. Among authors: price dl. Sci Transl Med. 2010 Jan 6;2(13):13ra1. doi: 10.1126/scitranslmed.3000337. Sci Transl Med. 2010. PMID: 20371462 Free PMC article.

4

Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.

Li T, Ma G, Cai H, Price DL, Wong PC. Li T, et al. Among authors: price dl. J Neurosci. 2003 Apr 15;23(8):3272-7. doi: 10.1523/JNEUROSCI.23-08-03272.2003. J Neurosci. 2003. PMID: 12716934 Free PMC article.

5

Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APP SWE.

Savonenko AV, Xu GM, Price DL, Borchelt DR, Markowska AL. Savonenko AV, et al. Among authors: price dl. Neurobiol Dis. 2003 Apr;12(3):194-211. doi: 10.1016/s0969-9961(02)00012-8. Neurobiol Dis. 2003. PMID: 12742740

6

APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.

Ma G, Li T, Price DL, Wong PC. Ma G, et al. Among authors: price dl. J Neurosci. 2005 Jan 5;25(1):192-8. doi: 10.1523/JNEUROSCI.3814-04.2005. J Neurosci. 2005. PMID: 15634781 Free PMC article.

7

Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.

Li T, Wen H, Brayton C, Laird FM, Ma G, Peng S, Placanica L, Wu TC, Crain BJ, Price DL, Eberhart CG, Wong PC. Li T, et al. Among authors: price dl. J Neurosci. 2007 Oct 3;27(40):10849-59. doi: 10.1523/JNEUROSCI.2152-07.2007. J Neurosci. 2007. PMID: 17913918 Free PMC article.

8

Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin.

Chiang PM, Fortna RR, Price DL, Li T, Wong PC. Chiang PM, et al. Among authors: price dl. Neurobiol Aging. 2012 Feb;33(2):277-85. doi: 10.1016/j.neurobiolaging.2009.12.028. Epub 2010 Apr 10. Neurobiol Aging. 2012. PMID: 20382452 Free PMC article.

9

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.

Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. Chiang PM, et al. Among authors: price dl. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16320-4. doi: 10.1073/pnas.1002176107. Epub 2010 Jul 26. Proc Natl Acad Sci U S A. 2010. PMID: 20660762 Free PMC article.

10

Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.

Shan X, Chiang PM, Price DL, Wong PC. Shan X, et al. Among authors: price dl. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16325-30. doi: 10.1073/pnas.1003459107. Epub 2010 Aug 24. Proc Natl Acad Sci U S A. 2010. PMID: 20736350 Free PMC article.

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