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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers.
Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL, Rasool S, Gurlo T, Butler P, Glabe CG. Kayed R, et al. Among authors: sarsoza f. Mol Neurodegener. 2007 Sep 26;2:18. doi: 10.1186/1750-1326-2-18. Mol Neurodegener. 2007. PMID: 17897471 Free PMC article.
A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain.
Sarsoza F, Saing T, Kayed R, Dahlin R, Dick M, Broadwater-Hollifield C, Mobley S, Lott I, Doran E, Gillen D, Anderson-Bergman C, Cribbs DH, Glabe C, Head E. Sarsoza F, et al. Acta Neuropathol. 2009 Oct;118(4):505-17. doi: 10.1007/s00401-009-0530-3. Epub 2009 Apr 10. Acta Neuropathol. 2009. PMID: 19360426 Free PMC article.
Synaptic proteins, neuropathology and cognitive status in the oldest-old.
Head E, Corrada MM, Kahle-Wrobleski K, Kim RC, Sarsoza F, Goodus M, Kawas CH. Head E, et al. Among authors: sarsoza f. Neurobiol Aging. 2009 Jul;30(7):1125-34. doi: 10.1016/j.neurobiolaging.2007.10.001. Epub 2007 Nov 14. Neurobiol Aging. 2009. PMID: 18006193 Free PMC article.
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