Neidle S - Search Results

1

Molecular dynamics and principal components analysis of human telomeric quadruplex multimers.

Haider S, Parkinson GN, Neidle S. Haider S, et al. Among authors: neidle s. Biophys J. 2008 Jul;95(1):296-311. doi: 10.1529/biophysj.107.120501. Epub 2008 Mar 28. Biophys J. 2008. PMID: 18375510 Free PMC article.

2

A molecular model for the enzyme cytochrome P450(17 alpha), a major target for the chemotherapy of prostatic cancer.

Laughton CA, Neidle S, Zvelebil MJ, Sternberg MJ. Laughton CA, et al. Among authors: neidle s. Biochem Biophys Res Commun. 1990 Sep 28;171(3):1160-7. doi: 10.1016/0006-291x(90)90806-x. Biochem Biophys Res Commun. 1990. PMID: 2222435

3

Molecular modeling studies on G-quadruplex complexes of telomerase inhibitors: structure-activity relationships.

Read MA, Wood AA, Harrison JR, Gowan SM, Kelland LR, Dosanjh HS, Neidle S. Read MA, et al. Among authors: neidle s. J Med Chem. 1999 Nov 4;42(22):4538-46. doi: 10.1021/jm990287e. J Med Chem. 1999. PMID: 10579817

4

Structure-activity relationships among guanine-quadruplex telomerase inhibitors.

Neidle S, Harrison RJ, Reszka AP, Read MA. Neidle S, et al. Pharmacol Ther. 2000 Mar;85(3):133-9. doi: 10.1016/s0163-7258(99)00065-0. Pharmacol Ther. 2000. PMID: 10739868 Review.

5

A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure.

Johansson E, Parkinson G, Neidle S. Johansson E, et al. Among authors: neidle s. J Mol Biol. 2000 Jul 14;300(3):551-61. doi: 10.1006/jmbi.2000.3907. J Mol Biol. 2000. PMID: 10884351

6

Crystal structure of FMN-dependent nitroreductase from Escherichia coli B: a prodrug-activating enzyme.

Parkinson GN, Skelly JV, Neidle S. Parkinson GN, et al. Among authors: neidle s. J Med Chem. 2000 Oct 5;43(20):3624-31. doi: 10.1021/jm000159m. J Med Chem. 2000. PMID: 11020276

7

Structural characterization of a guanine-quadruplex ligand complex.

Read MA, Neidle S. Read MA, et al. Among authors: neidle s. Biochemistry. 2000 Nov 7;39(44):13422-32. doi: 10.1021/bi001584k. Biochemistry. 2000. PMID: 11063579

8

A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.

Mann J, Baron A, Opoku-Boahen Y, Johansson E, Parkinson G, Kelland LR, Neidle S. Mann J, et al. Among authors: neidle s. J Med Chem. 2001 Jan 18;44(2):138-44. doi: 10.1021/jm000297b. J Med Chem. 2001. PMID: 11170623

9

G-quadruplexes as therapeutic targets.

Neidle S, Read MA. Neidle S, et al. Biopolymers. 2000-2001;56(3):195-208. doi: 10.1002/1097-0282(2000)56:3<195::AID-BIP10009>3.0.CO;2-5. Biopolymers. 2000. PMID: 11745111 Review.

10

Crystal structure of parallel quadruplexes from human telomeric DNA.

Parkinson GN, Lee MP, Neidle S. Parkinson GN, et al. Among authors: neidle s. Nature. 2002 Jun 20;417(6891):876-80. doi: 10.1038/nature755. Epub 2002 May 26. Nature. 2002. PMID: 12050675

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