Sharples RA - Search Results

1

Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.

Price KA, Filiz G, Caragounis A, Du T, Laughton KM, Masters CL, Sharples RA, Hill AF, Li QX, Donnelly PS, Barnham KJ, Crouch PJ, White AR. Price KA, et al. Among authors: sharples ra. Int J Biochem Cell Biol. 2008;40(9):1901-17. doi: 10.1016/j.biocel.2008.01.033. Epub 2008 Feb 12. Int J Biochem Cell Biol. 2008. PMID: 18346929

2

Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.

White AR, Du T, Laughton KM, Volitakis I, Sharples RA, Xilinas ME, Hoke DE, Holsinger RM, Evin G, Cherny RA, Hill AF, Barnham KJ, Li QX, Bush AI, Masters CL. White AR, et al. Among authors: sharples ra. J Biol Chem. 2006 Jun 30;281(26):17670-80. doi: 10.1074/jbc.M602487200. Epub 2006 Apr 28. J Biol Chem. 2006. PMID: 16648635 Free article.

3

Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.

Caragounis A, Du T, Filiz G, Laughton KM, Volitakis I, Sharples RA, Cherny RA, Masters CL, Drew SC, Hill AF, Li QX, Crouch PJ, Barnham KJ, White AR. Caragounis A, et al. Among authors: sharples ra. Biochem J. 2007 Nov 1;407(3):435-50. doi: 10.1042/BJ20070579. Biochem J. 2007. PMID: 17680773 Free PMC article.

4

Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide.

Donnelly PS, Caragounis A, Du T, Laughton KM, Volitakis I, Cherny RA, Sharples RA, Hill AF, Li QX, Masters CL, Barnham KJ, White AR. Donnelly PS, et al. Among authors: sharples ra. J Biol Chem. 2008 Feb 22;283(8):4568-77. doi: 10.1074/jbc.M705957200. Epub 2007 Dec 17. J Biol Chem. 2008. PMID: 18086681 Free article.

5

Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.

Sharples RA, Vella LJ, Nisbet RM, Naylor R, Perez K, Barnham KJ, Masters CL, Hill AF. Sharples RA, et al. FASEB J. 2008 May;22(5):1469-78. doi: 10.1096/fj.07-9357com. Epub 2008 Jan 2. FASEB J. 2008. PMID: 18171695

6

Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture.

Lawson VA, Vella LJ, Stewart JD, Sharples RA, Klemm H, Machalek DM, Masters CL, Cappai R, Collins SJ, Hill AF. Lawson VA, et al. Among authors: sharples ra. Int J Biochem Cell Biol. 2008;40(12):2793-801. doi: 10.1016/j.biocel.2008.05.024. Epub 2008 Jun 11. Int J Biochem Cell Biol. 2008. PMID: 18590830

7

Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug Cu(II)(atsm).

Cheng L, Quek CY, Hung LW, Sharples RA, Sherratt NA, Barnham KJ, Hill AF. Cheng L, et al. Among authors: sharples ra. Sci Rep. 2016 Mar 1;6:22398. doi: 10.1038/srep22398. Sci Rep. 2016. PMID: 26928495 Free PMC article.

8

Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.

Evin G, Canterford LD, Hoke DE, Sharples RA, Culvenor JG, Masters CL. Evin G, et al. Among authors: sharples ra. Biochemistry. 2005 Mar 22;44(11):4332-41. doi: 10.1021/bi0481702. Biochemistry. 2005. PMID: 15766262

9

Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.

Cappai R, Leck SL, Tew DJ, Williamson NA, Smith DP, Galatis D, Sharples RA, Curtain CC, Ali FE, Cherny RA, Culvenor JG, Bottomley SP, Masters CL, Barnham KJ, Hill AF. Cappai R, et al. Among authors: sharples ra. FASEB J. 2005 Aug;19(10):1377-9. doi: 10.1096/fj.04-3437fje. Epub 2005 Jun 9. FASEB J. 2005. PMID: 15946991

10

Packaging of prions into exosomes is associated with a novel pathway of PrP processing.

Vella LJ, Sharples RA, Lawson VA, Masters CL, Cappai R, Hill AF. Vella LJ, et al. Among authors: sharples ra. J Pathol. 2007 Apr;211(5):582-590. doi: 10.1002/path.2145. J Pathol. 2007. PMID: 17334982

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