Chazin WJ - Search Results

1

S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway.

Ghavami S, Rashedi I, Dattilo BM, Eshraghi M, Chazin WJ, Hashemi M, Wesselborg S, Kerkhoff C, Los M. Ghavami S, et al. Among authors: chazin wj. J Leukoc Biol. 2008 Jun;83(6):1484-92. doi: 10.1189/jlb.0607397. Epub 2008 Mar 13. J Leukoc Biol. 2008. PMID: 18339893 Free PMC article.

2

The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units.

Dattilo BM, Fritz G, Leclerc E, Kooi CW, Heizmann CW, Chazin WJ. Dattilo BM, et al. Among authors: chazin wj. Biochemistry. 2007 Jun 12;46(23):6957-70. doi: 10.1021/bi7003735. Epub 2007 May 18. Biochemistry. 2007. PMID: 17508727 Free PMC article.

3

An iron-sulfur cluster in the C-terminal domain of the p58 subunit of human DNA primase.

Weiner BE, Huang H, Dattilo BM, Nilges MJ, Fanning E, Chazin WJ. Weiner BE, et al. Among authors: chazin wj. J Biol Chem. 2007 Nov 16;282(46):33444-33451. doi: 10.1074/jbc.M705826200. Epub 2007 Sep 24. J Biol Chem. 2007. PMID: 17893144 Free article.

4

S100A8/9 induces cell death via a novel, RAGE-independent pathway that involves selective release of Smac/DIABLO and Omi/HtrA2.

Ghavami S, Kerkhoff C, Chazin WJ, Kadkhoda K, Xiao W, Zuse A, Hashemi M, Eshraghi M, Schulze-Osthoff K, Klonisch T, Los M. Ghavami S, et al. Among authors: chazin wj. Biochim Biophys Acta. 2008 Feb;1783(2):297-311. doi: 10.1016/j.bbamcr.2007.10.015. Epub 2007 Nov 7. Biochim Biophys Acta. 2008. PMID: 18060880 Free article.

5

S100A8/A9: a Janus-faced molecule in cancer therapy and tumorgenesis.

Ghavami S, Chitayat S, Hashemi M, Eshraghi M, Chazin WJ, Halayko AJ, Kerkhoff C. Ghavami S, et al. Among authors: chazin wj. Eur J Pharmacol. 2009 Dec 25;625(1-3):73-83. doi: 10.1016/j.ejphar.2009.08.044. Epub 2009 Oct 14. Eur J Pharmacol. 2009. PMID: 19835859 Review.

6

S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3.

Ghavami S, Eshragi M, Ande SR, Chazin WJ, Klonisch T, Halayko AJ, McNeill KD, Hashemi M, Kerkhoff C, Los M. Ghavami S, et al. Among authors: chazin wj. Cell Res. 2010 Mar;20(3):314-31. doi: 10.1038/cr.2009.129. Epub 2009 Nov 24. Cell Res. 2010. PMID: 19935772 Free PMC article.

7

Structural basis for ligand recognition and activation of RAGE.

Koch M, Chitayat S, Dattilo BM, Schiefner A, Diez J, Chazin WJ, Fritz G. Koch M, et al. Among authors: chazin wj. Structure. 2010 Oct 13;18(10):1342-52. doi: 10.1016/j.str.2010.05.017. Structure. 2010. PMID: 20947022 Free PMC article.

8

Metal chelation and inhibition of bacterial growth in tissue abscesses.

Corbin BD, Seeley EH, Raab A, Feldmann J, Miller MR, Torres VJ, Anderson KL, Dattilo BM, Dunman PM, Gerads R, Caprioli RM, Nacken W, Chazin WJ, Skaar EP. Corbin BD, et al. Among authors: chazin wj. Science. 2008 Feb 15;319(5865):962-5. doi: 10.1126/science.1152449. Science. 2008. PMID: 18276893

9

The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis.

Sunahori K, Yamamura M, Yamana J, Takasugi K, Kawashima M, Yamamoto H, Chazin WJ, Nakatani Y, Yui S, Makino H. Sunahori K, et al. Among authors: chazin wj. Arthritis Res Ther. 2006;8(3):R69. doi: 10.1186/ar1939. Epub 2006 Apr 13. Arthritis Res Ther. 2006. PMID: 16613612 Free PMC article.

10

Stable RAGE-heparan sulfate complexes are essential for signal transduction.

Xu D, Young JH, Krahn JM, Song D, Corbett KD, Chazin WJ, Pedersen LC, Esko JD. Xu D, et al. Among authors: chazin wj. ACS Chem Biol. 2013 Jul 19;8(7):1611-20. doi: 10.1021/cb4001553. Epub 2013 May 28. ACS Chem Biol. 2013. PMID: 23679870 Free PMC article.

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