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Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells.
Kim DH, Burgess AP, Li M, Tsenovoy PL, Addabbo F, McClung JA, Puri N, Abraham NG. Kim DH, et al. Among authors: tsenovoy pl. J Pharmacol Exp Ther. 2008 Jun;325(3):833-40. doi: 10.1124/jpet.107.135285. Epub 2008 Mar 11. J Pharmacol Exp Ther. 2008. PMID: 18334666
Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway.
Cao J, Tsenovoy PL, Thompson EA, Falck JR, Touchon R, Sodhi K, Rezzani R, Shapiro JI, Abraham NG. Cao J, et al. Among authors: tsenovoy pl. Prostaglandins Other Lipid Mediat. 2015 Jan-Mar;116-117:76-86. doi: 10.1016/j.prostaglandins.2015.01.002. Epub 2015 Feb 9. Prostaglandins Other Lipid Mediat. 2015. PMID: 25677507 Free PMC article.
Heme oxygenase: a target gene for anti-diabetic and obesity.
Abraham NG, Tsenovoy PL, McClung J, Drummond GS. Abraham NG, et al. Among authors: tsenovoy pl. Curr Pharm Des. 2008;14(5):412-21. doi: 10.2174/138161208783597371. Curr Pharm Des. 2008. PMID: 18289068 Review.