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Ghrelin alone or co-administered with GHRH or CRH increases non-REM sleep and decreases REM sleep in young males.
Psychoneuroendocrinology. 2008 May;33(4):497-506. doi: 10.1016/j.psyneuen.2008.01.008. Epub 2008 Mar 10.
Psychoneuroendocrinology. 2008.
PMID: 18329818
Clinical Trial.
Ghrelin enhances the nocturnal secretion of cortisol and growth hormone in young females without influencing sleep.
Kluge M, Schüssler P, Zuber V, Kleyer S, Yassouridis A, Dresler M, Uhr M, Steiger A.
Kluge M, et al. Among authors: kleyer s.
Psychoneuroendocrinology. 2007 Sep-Nov;32(8-10):1079-85. doi: 10.1016/j.psyneuen.2007.09.001. Epub 2007 Oct 22.
Psychoneuroendocrinology. 2007.
PMID: 17945435
Clinical Trial.
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Ghrelin plasma levels are not altered in major depression.
Kluge M, Schussler P, Schmid D, Uhr M, Kleyer S, Yassouridis A, Steiger A.
Kluge M, et al. Among authors: kleyer s.
Neuropsychobiology. 2009;59(4):199-204. doi: 10.1159/000223731. Epub 2009 Jun 10.
Neuropsychobiology. 2009.
PMID: 19521111
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Ghrelin increases slow wave sleep and stage 2 sleep and decreases stage 1 sleep and REM sleep in elderly men but does not affect sleep in elderly women.
Kluge M, Gazea M, Schüssler P, Genzel L, Dresler M, Kleyer S, Uhr M, Yassouridis A, Steiger A.
Kluge M, et al. Among authors: kleyer s.
Psychoneuroendocrinology. 2010 Feb;35(2):297-304. doi: 10.1016/j.psyneuen.2009.07.007. Epub 2009 Aug 3.
Psychoneuroendocrinology. 2010.
PMID: 19647945
Clinical Trial.
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