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A small molecule inhibitor of alpha4 integrin-dependent cell migration.
Lee J, Hong J, Nam TG, Peters EC, Orth AP, Geierstanger BH, Goldfinger LE, Ginsberg MH, Cho CY, Schultz PG. Lee J, et al. Among authors: orth ap. Bioorg Med Chem. 2009 Feb 1;17(3):977-80. doi: 10.1016/j.bmc.2008.02.067. Epub 2008 Feb 26. Bioorg Med Chem. 2009. PMID: 18329275 Free PMC article.
Genome-wide functional analysis of human cell-cycle regulators.
Mukherji M, Bell R, Supekova L, Wang Y, Orth AP, Batalov S, Miraglia L, Huesken D, Lange J, Martin C, Sahasrabudhe S, Reinhardt M, Natt F, Hall J, Mickanin C, Labow M, Chanda SK, Cho CY, Schultz PG. Mukherji M, et al. Among authors: orth ap. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14819-24. doi: 10.1073/pnas.0604320103. Epub 2006 Sep 25. Proc Natl Acad Sci U S A. 2006. PMID: 17001007 Free PMC article.
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Gonzalez R, Jennings LL, Knuth M, Orth AP, Klock HE, Ou W, Feuerhelm J, Hull MV, Koesema E, Wang Y, Zhang J, Wu C, Cho CY, Su AI, Batalov S, Chen H, Johnson K, Laffitte B, Nguyen DG, Snyder EY, Schultz PG, Harris JL, Lesley SA. Gonzalez R, et al. Among authors: orth ap. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3552-7. doi: 10.1073/pnas.0914019107. Epub 2010 Feb 2. Proc Natl Acad Sci U S A. 2010. PMID: 20133595 Free PMC article.
A genomic screen identifies TYRO3 as a MITF regulator in melanoma.
Zhu S, Wurdak H, Wang Y, Galkin A, Tao H, Li J, Lyssiotis CA, Yan F, Tu BP, Miraglia L, Walker J, Sun F, Orth A, Schultz PG, Wu X. Zhu S, et al. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17025-30. doi: 10.1073/pnas.0909292106. Epub 2009 Sep 23. Proc Natl Acad Sci U S A. 2009. PMID: 19805117 Free PMC article.
A functional genomics approach to the mode of action of apratoxin A.
Luesch H, Chanda SK, Raya RM, DeJesus PD, Orth AP, Walker JR, Izpisúa Belmonte JC, Schultz PG. Luesch H, et al. Among authors: orth ap. Nat Chem Biol. 2006 Mar;2(3):158-67. doi: 10.1038/nchembio769. Epub 2006 Feb 12. Nat Chem Biol. 2006. PMID: 16474387
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.
Wurdak H, Zhu S, Romero A, Lorger M, Watson J, Chiang CY, Zhang J, Natu VS, Lairson LL, Walker JR, Trussell CM, Harsh GR, Vogel H, Felding-Habermann B, Orth AP, Miraglia LJ, Rines DR, Skirboll SL, Schultz PG. Wurdak H, et al. Among authors: orth ap. Cell Stem Cell. 2010 Jan 8;6(1):37-47. doi: 10.1016/j.stem.2009.11.002. Cell Stem Cell. 2010. PMID: 20085741 Free article.
60 results