Ikeda S - Search Results

1

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2).

Asano Y, Kitamura S, Ohra T, Itoh F, Kajino M, Tamura T, Kaneko M, Ikeda S, Igata H, Kawamoto T, Sogabe S, Matsumoto S, Tanaka T, Yamaguchi M, Kimura H, Fukumoto S. Asano Y, et al. Among authors: ikeda s. Bioorg Med Chem. 2008 Apr 15;16(8):4699-714. doi: 10.1016/j.bmc.2008.02.028. Epub 2008 Feb 13. Bioorg Med Chem. 2008. PMID: 18313930

2

Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure.

Okawa T, Aramaki Y, Yamamoto M, Kobayashi T, Fukumoto S, Toyoda Y, Henta T, Hata A, Ikeda S, Kaneko M, Hoffman ID, Sang BC, Zou H, Kawamoto T. Okawa T, et al. Among authors: ikeda s. J Med Chem. 2017 Aug 24;60(16):6942-6990. doi: 10.1021/acs.jmedchem.7b00443. Epub 2017 Aug 3. J Med Chem. 2017. PMID: 28699740

3

In vitro and in vivo pharmacology of a structurally novel Na+-H+ exchange inhibitor, T-162559.

Kusumoto K, Igata H, Abe A, Ikeda S, Tsuboi A, Imamiya E, Fukumoto S, Shiraishi M, Watanabe T. Kusumoto K, et al. Among authors: ikeda s. Br J Pharmacol. 2002 Apr;135(8):1995-2003. doi: 10.1038/sj.bjp.0704647. Br J Pharmacol. 2002. PMID: 11959803 Free PMC article.

4

A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice.

Yashiro H, Takagahara S, Tamura YO, Miyahisa I, Matsui J, Suzuki H, Ikeda S, Watanabe M. Yashiro H, et al. Among authors: ikeda s. PLoS One. 2016 Nov 10;11(11):e0166198. doi: 10.1371/journal.pone.0166198. eCollection 2016. PLoS One. 2016. PMID: 27832159 Free PMC article.

5

Effects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y ₂ agonist, on cardiomyocytes in neonatal rats.

Sakuma K, Nakagawa H, Oikawa T, Noda M, Ikeda S. Sakuma K, et al. Among authors: ikeda s. Sci Rep. 2017 Jul 20;7(1):6050. doi: 10.1038/s41598-017-06481-9. Sci Rep. 2017. PMID: 28729619 Free PMC article.

6

TAK-272 (imarikiren), a novel renin inhibitor, improves cardiac remodeling and mortality in a murine heart failure model.

Hara T, Nishimura S, Yamamoto T, Kajimoto Y, Kusumoto K, Kanagawa R, Ikeda S, Nishimoto T. Hara T, et al. Among authors: ikeda s. PLoS One. 2018 Aug 9;13(8):e0202176. doi: 10.1371/journal.pone.0202176. eCollection 2018. PLoS One. 2018. PMID: 30092100 Free PMC article.

7

Effects of compound-326, a selective delta-5 desaturase inhibitor, in ApoE knockout mice with two different protocols for atherosclerosis development.

Nagase H, Takagahara S, Satomi Y, Ando A, Kubo K, Ikeda S. Nagase H, et al. Among authors: ikeda s. J Pharm Pharm Sci. 2021;24:71-83. doi: 10.18433/jpps31389. J Pharm Pharm Sci. 2021. PMID: 33600308 Free article.

8

A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice.

Takagahara S, Shinohara H, Itokawa S, Satomi Y, Ando A, Yamamoto T, Suzuki H, Fujimoto T, Kubo K, Ikeda S. Takagahara S, et al. Among authors: ikeda s. J Pharmacol Exp Ther. 2019 Nov;371(2):290-298. doi: 10.1124/jpet.119.259846. Epub 2019 Sep 5. J Pharmacol Exp Ther. 2019. PMID: 31488602

9

Development of antibody-siRNA conjugate targeted to cardiac and skeletal muscles.

Sugo T, Terada M, Oikawa T, Miyata K, Nishimura S, Kenjo E, Ogasawara-Shimizu M, Makita Y, Imaichi S, Murata S, Otake K, Kikuchi K, Teratani M, Masuda Y, Kamei T, Takagahara S, Ikeda S, Ohtaki T, Matsumoto H. Sugo T, et al. Among authors: ikeda s. J Control Release. 2016 Sep 10;237:1-13. doi: 10.1016/j.jconrel.2016.06.036. Epub 2016 Jun 29. J Control Release. 2016. PMID: 27369865

10

Acute and chronic effects of exercise on mRNA expression in the skeletal muscle of two mouse models of peripheral artery disease.

Nagase H, Yao S, Ikeda S. Nagase H, et al. Among authors: ikeda s. PLoS One. 2017 Aug 3;12(8):e0182456. doi: 10.1371/journal.pone.0182456. eCollection 2017. PLoS One. 2017. PMID: 28771574 Free PMC article.

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