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A new strategy for the preparation of peptide-targeted radiopharmaceuticals based on an fmoc-lysine-derived single amino acid chelate (SAAC). automated solid-phase synthesis, NMR characterization, and in vitro screening of fMLF(SAAC)G and fMLF[(SAAC-Re(CO)3)+]G.
Stephenson KA, Zubieta J, Banerjee SR, Levadala MK, Taggart L, Ryan L, McFarlane N, Boreham DR, Maresca KP, Babich JW, Valliant JF. Stephenson KA, et al. Among authors: babich jw. Bioconjug Chem. 2004 Jan-Feb;15(1):128-36. doi: 10.1021/bc034128s. Bioconjug Chem. 2004. PMID: 14733592
A new strategy for the preparation of peptide-targeted technetium and rhenium radiopharmaceuticals. The automated solid-phase synthesis, characterization, labeling, and screening of a peptide-ligand library targeted at the formyl peptide receptor.
Stephenson KA, Banerjee SR, Sogbein OO, Levadala MK, McFarlane N, Boreham DR, Maresca KP, Babich JW, Zubieta J, Valliant JF. Stephenson KA, et al. Among authors: babich jw. Bioconjug Chem. 2005 Sep-Oct;16(5):1189-95. doi: 10.1021/bc0500591. Bioconjug Chem. 2005. PMID: 16173797
A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents.
Armstrong AF, Oakley N, Parker S, Causey PW, Lemon J, Capretta A, Zimmerman C, Joyal J, Appoh F, Zubieta J, Babich JW, Singh G, Valliant JF. Armstrong AF, et al. Among authors: babich jw. Chem Commun (Camb). 2008 Nov 21;(43):5532-4. doi: 10.1039/b810706h. Epub 2008 Sep 24. Chem Commun (Camb). 2008. PMID: 18997942
Synthesis and characterization of rhenium and technetium-99m labeled insulin.
Sundararajan C, Besanger TR, Labiris R, Guenther KJ, Strack T, Garafalo R, Kawabata TT, Finco-Kent D, Zubieta J, Babich JW, Valliant JF. Sundararajan C, et al. Among authors: babich jw. J Med Chem. 2010 Mar 25;53(6):2612-21. doi: 10.1021/jm100096c. J Med Chem. 2010. PMID: 20235598
204 results