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Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil.
Shitara Y, Hirano M, Sato H, Sugiyama Y. Shitara Y, et al. Among authors: sugiyama y. J Pharmacol Exp Ther. 2004 Oct;311(1):228-36. doi: 10.1124/jpet.104.068536. Epub 2004 Jun 11. J Pharmacol Exp Ther. 2004. PMID: 15194707
2,702 results