Rajakulendran T - Search Results

1

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.

Rajakulendran T, Sahmi M, Kurinov I, Tyers M, Therrien M, Sicheri F. Rajakulendran T, et al. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2836-41. doi: 10.1073/pnas.0709705105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287031 Free PMC article.

2

A dimerization-dependent mechanism drives RAF catalytic activation.

Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M. Rajakulendran T, et al. Nature. 2009 Sep 24;461(7263):542-5. doi: 10.1038/nature08314. Epub 2009 Sep 2. Nature. 2009. PMID: 19727074

3

Allosteric protein kinase regulation by pseudokinases: insights from STRAD.

Rajakulendran T, Sicheri F. Rajakulendran T, et al. Sci Signal. 2010 Mar 2;3(111):pe8. doi: 10.1126/scisignal.3111pe8. Sci Signal. 2010. PMID: 20197543 Review.

4

Mechanistic principles of RAF kinase signaling.

Udell CM, Rajakulendran T, Sicheri F, Therrien M. Udell CM, et al. Among authors: rajakulendran t. Cell Mol Life Sci. 2011 Feb;68(4):553-65. doi: 10.1007/s00018-010-0520-6. Epub 2010 Sep 6. Cell Mol Life Sci. 2011. PMID: 20820846 Free PMC article. Review.

5

Inhibition of RAS function through targeting an allosteric regulatory site.

Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, Okur MN, Dementieva I, Sicheri F, Therrien M, Hancock JF, Ikura M, Koide S, O'Bryan JP. Spencer-Smith R, et al. Among authors: rajakulendran t. Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7. Nat Chem Biol. 2017. PMID: 27820802 Free PMC article.

6

Bench to bedside: mechanistic principles of targeting the RAF kinase in melanoma.

Rajakulendran T, Adam DN. Rajakulendran T, et al. Int J Dermatol. 2014 Dec;53(12):1428-33. doi: 10.1111/ijd.12724. Epub 2014 Oct 14. Int J Dermatol. 2014. PMID: 25311997 Review.

7

Spotlight on pembrolizumab in the treatment of advanced melanoma.

Rajakulendran T, Adam DN. Rajakulendran T, et al. Drug Des Devel Ther. 2015 Jun 4;9:2883-6. doi: 10.2147/DDDT.S78036. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26082618 Free PMC article. Review.

8

A Vision for an Academic Career Mentorship Program for Canadian Dermatology Residents.

Ghazawi FM, Lefrançois P, Xie P, Rajakulendran T, Copley M, Drucker AM, Alavi A, Zhou Y, Litvinov IV. Ghazawi FM, et al. Among authors: rajakulendran t. J Cutan Med Surg. 2019 Jan/Feb;23(1):123-124. doi: 10.1177/1203475418803067. J Cutan Med Surg. 2019. PMID: 30789036 No abstract available.

9

Ecologically mediated differences in electric organ discharge drive evolution in a sodium channel gene in South American electric fishes.

Hauser FE, Xiao D, Van Nynatten A, Brochu-De Luca KK, Rajakulendran T, Elbassiouny AE, Sivanesan H, Sivananthan P, Crampton WGR, Lovejoy NR. Hauser FE, et al. Among authors: rajakulendran t. Biol Lett. 2024 Feb;20(2):20230480. doi: 10.1098/rsbl.2023.0480. Epub 2024 Feb 28. Biol Lett. 2024. PMID: 38412964

10

Supporting Female Survivors of Gender-Based Violence Experiencing Homelessness: Outcomes of a Health Promotion Psychoeducation Group Intervention.

Bani-Fatemi A, Malta M, Noble A, Wang W, Rajakulendran T, Kahan D, Stergiopoulos V. Bani-Fatemi A, et al. Among authors: rajakulendran t. Front Psychiatry. 2020 Dec 9;11:601540. doi: 10.3389/fpsyt.2020.601540. eCollection 2020. Front Psychiatry. 2020. PMID: 33362610 Free PMC article.

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