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464 results

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Page 1
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.
Polisecki E, Muallem H, Maeda N, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Westendorp RG, de Craen AJ, Buckley BM, Ordovas JM, Schaefer EJ; Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators. Polisecki E, et al. Among authors: de craen aj. Atherosclerosis. 2008 Sep;200(1):109-14. doi: 10.1016/j.atherosclerosis.2007.12.004. Epub 2008 Feb 7. Atherosclerosis. 2008. PMID: 18261733 Free PMC article. Clinical Trial.
Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population.
Polisecki E, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ; PROSPER Study Group. Polisecki E, et al. Among authors: de craen aj. Atherosclerosis. 2008 Sep;200(1):95-101. doi: 10.1016/j.atherosclerosis.2007.12.005. Epub 2008 Feb 8. Atherosclerosis. 2008. PMID: 18262190 Free PMC article. Clinical Trial.
Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly.
Polisecki E, Peter I, Simon JS, Hegele RA, Robertson M, Ford I, Shepherd J, Packard C, Jukema JW, de Craen AJ, Westendorp RG, Buckley BM, Schaefer EJ; Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators. Polisecki E, et al. Among authors: de craen aj. J Lipid Res. 2010 May;51(5):1201-7. doi: 10.1194/jlr.P001172. Epub 2009 Sep 14. J Lipid Res. 2010. PMID: 19752398 Free PMC article. Clinical Trial.
Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly.
Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ. Akao H, et al. Among authors: de craen aj. Atherosclerosis. 2012 Feb;220(2):413-7. doi: 10.1016/j.atherosclerosis.2011.09.028. Epub 2011 Sep 21. Atherosclerosis. 2012. PMID: 22189199 Clinical Trial.
KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.
Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ. Akao H, et al. Among authors: de craen aj. Atherosclerosis. 2012 Feb;220(2):456-62. doi: 10.1016/j.atherosclerosis.2011.11.037. Epub 2011 Dec 7. Atherosclerosis. 2012. PMID: 22192511 Clinical Trial.
In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study.
Postmus I, Johnson PC, Trompet S, de Craen AJ, Slagboom PE, Devlin JJ, Shiffman D, Sacks FM, Kearney PM, Stott DJ, Buckley BM, Sattar N, Ford I, Westendorp RG, Jukema JW. Postmus I, et al. Among authors: de craen aj. Atherosclerosis. 2014 Jul;235(1):58-64. doi: 10.1016/j.atherosclerosis.2014.04.009. Epub 2014 Apr 26. Atherosclerosis. 2014. PMID: 24816038 Clinical Trial.
ABCA1 gene variation and heart disease risk reduction in the elderly during pravastatin treatment.
Akao H, Polisecki E, Schaefer EJ, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Packard C, Buckley BM, Kajinami K; PROspective Study of Pravastatin in the Elderly at Risk Investigator. Akao H, et al. Among authors: de craen aj. Atherosclerosis. 2014 Jul;235(1):176-81. doi: 10.1016/j.atherosclerosis.2014.04.030. Epub 2014 May 8. Atherosclerosis. 2014. PMID: 24854628 Free PMC article. Clinical Trial.
Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk.
Welsh P, Murray HM, Ford I, Trompet S, de Craen AJ, Jukema JW, Stott DJ, McInnes IB, Packard CJ, Westendorp RG, Sattar N; PROSPER Study Group. Welsh P, et al. Among authors: de craen aj. Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2338-44. doi: 10.1161/ATVBAHA.111.231795. Epub 2011 Jul 14. Arterioscler Thromb Vasc Biol. 2011. PMID: 21757655 Free article. Clinical Trial.
464 results