Worthington AS - Search Results

1

An orthogonal purification strategy for isolating crosslinked domains of modular synthases.

Haushalter RW, Worthington AS, Hur GH, Burkart MD. Haushalter RW, et al. Among authors: worthington as. Bioorg Med Chem Lett. 2008 May 15;18(10):3039-42. doi: 10.1016/j.bmcl.2008.01.026. Epub 2008 Jan 11. Bioorg Med Chem Lett. 2008. PMID: 18249538 Free PMC article.

2

Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase.

Kapur S, Worthington A, Tang Y, Cane DE, Burkart MD, Khosla C. Kapur S, et al. Bioorg Med Chem Lett. 2008 May 15;18(10):3034-8. doi: 10.1016/j.bmcl.2008.01.073. Epub 2008 Jan 24. Bioorg Med Chem Lett. 2008. PMID: 18243693 Free PMC article.

3

Probing the compatibility of type II ketosynthase-carrier protein partners.

Worthington AS, Hur GH, Meier JL, Cheng Q, Moore BS, Burkart MD. Worthington AS, et al. Chembiochem. 2008 Sep 1;9(13):2096-103. doi: 10.1002/cbic.200800198. Chembiochem. 2008. PMID: 18666307 Free PMC article.

4

Mechanism-based crosslinking as a gauge for functional interaction of modular synthases.

Worthington AS, Porter DF, Burkart MD. Worthington AS, et al. Org Biomol Chem. 2010 Apr 21;8(8):1769-72. doi: 10.1039/b925966j. Org Biomol Chem. 2010. PMID: 20449476

5

Activity-guided engineering of natural product carrier proteins.

Worthington AS, Hur GH, Burkart MD. Worthington AS, et al. Mol Biosyst. 2011 Feb;7(2):365-70. doi: 10.1039/c0mb00251h. Epub 2010 Dec 24. Mol Biosyst. 2011. PMID: 21184004

6

One-pot chemo-enzymatic synthesis of reporter-modified proteins.

Worthington AS, Burkart MD. Worthington AS, et al. Org Biomol Chem. 2006 Jan 7;4(1):44-6. doi: 10.1039/b512735a. Epub 2005 Nov 24. Org Biomol Chem. 2006. PMID: 16357994

7

The old is new again: asparagine oxidation in calcium-dependent antibiotic biosynthesis.

Worthington AS, Burkart MD. Worthington AS, et al. ACS Chem Biol. 2007 Mar 20;2(3):152-4. doi: 10.1021/cb700053g. ACS Chem Biol. 2007. PMID: 17373761 Review.

8

Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis.

Worthington AS, Rivera H, Torpey JW, Alexander MD, Burkart MD. Worthington AS, et al. ACS Chem Biol. 2006 Dec 20;1(11):687-91. doi: 10.1021/cb6003965. ACS Chem Biol. 2006. PMID: 17184132

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