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Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice.
Schurigt U, Hummel KM, Petrow PK, Gajda M, Stöckigt R, Middel P, Zwerina J, Janik T, Bernhardt R, Schüler S, Scharnweber D, Beckmann F, Saftig P, Kollias G, Schett G, Wiederanders B, Bräuer R. Schurigt U, et al. Among authors: schett g. Arthritis Rheum. 2008 Feb;58(2):422-34. doi: 10.1002/art.23224. Arthritis Rheum. 2008. PMID: 18240253 Free article.
Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: regulation of expression and activation by interleukin-1 and tumor necrosis factor alpha.
Redlich K, Kiener HP, Schett G, Tohidast-Akrad M, Selzer E, Radda I, Stummvoll GH, Steiner CW, Gröger M, Bitzan P, Zenz P, Smolen JS, Steiner G. Redlich K, et al. Among authors: schett g. Arthritis Rheum. 2001 Feb;44(2):266-74. doi: 10.1002/1529-0131(200102)44:2<266::AID-ANR43>3.0.CO;2-G. Arthritis Rheum. 2001. PMID: 11229456 Free article.
Adenovirus-based overexpression of tissue inhibitor of metalloproteinases 1 reduces tissue damage in the joints of tumor necrosis factor alpha transgenic mice.
Schett G, Hayer S, Tohidast-Akrad M, Schmid BJ, Lang S, Türk B, Kainberger F, Haralambous S, Kollias G, Newby AC, Xu Q, Steiner G, Smolen J. Schett G, et al. Arthritis Rheum. 2001 Dec;44(12):2888-98. doi: 10.1002/1529-0131(200112)44:12<2888::aid-art477>3.0.co;2-3. Arthritis Rheum. 2001. PMID: 11762950 Free article.
Osteoclasts are essential for TNF-alpha-mediated joint destruction.
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G. Redlich K, et al. Among authors: schett g. J Clin Invest. 2002 Nov;110(10):1419-27. doi: 10.1172/JCI15582. J Clin Invest. 2002. PMID: 12438440 Free PMC article.
Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction.
Zwerina J, Hayer S, Tohidast-Akrad M, Bergmeister H, Redlich K, Feige U, Dunstan C, Kollias G, Steiner G, Smolen J, Schett G. Zwerina J, et al. Among authors: schett g. Arthritis Rheum. 2004 Jan;50(1):277-90. doi: 10.1002/art.11487. Arthritis Rheum. 2004. PMID: 14730626 Free article.
Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis.
Redlich K, Görtz B, Hayer S, Zwerina J, Doerr N, Kostenuik P, Bergmeister H, Kollias G, Steiner G, Smolen JS, Schett G. Redlich K, et al. Among authors: schett g. Am J Pathol. 2004 Feb;164(2):543-55. doi: 10.1016/S0002-9440(10)63144-6. Am J Pathol. 2004. PMID: 14742260 Free PMC article.
Overexpression of tumor necrosis factor causes bilateral sacroiliitis.
Redlich K, Görtz B, Hayer S, Zwerina J, Kollias G, Steiner G, Smolen JS, Schett G. Redlich K, et al. Among authors: schett g. Arthritis Rheum. 2004 Mar;50(3):1001-5. doi: 10.1002/art.20194. Arthritis Rheum. 2004. PMID: 15022345 Free article. No abstract available.
Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation.
Görtz B, Hayer S, Redlich K, Zwerina J, Tohidast-Akrad M, Tuerk B, Hartmann C, Kollias G, Steiner G, Smolen JS, Schett G. Görtz B, et al. Among authors: schett g. J Bone Miner Res. 2004 Jun;19(6):990-8. doi: 10.1359/JBMR.040205. Epub 2004 Feb 9. J Bone Miner Res. 2004. PMID: 15125796 Free article.
1,083 results