Leof EB - Search Results

1

Histologic studies of the intraocular toxicity of imatinib mesylate in rabbits.

Kitzmann AS, Baratz KH, Mohney BG, Pulido JS, Cameron JD, Lee ES, Leof EB. Kitzmann AS, et al. Among authors: leof eb. Eye (Lond). 2008 May;22(5):712-4. doi: 10.1038/sj.eye.6703092. Epub 2008 Feb 1. Eye (Lond). 2008. PMID: 18239681

2

Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis.

Daniels CE, Wilkes MC, Edens M, Kottom TJ, Murphy SJ, Limper AH, Leof EB. Daniels CE, et al. Among authors: leof eb. J Clin Invest. 2004 Nov;114(9):1308-16. doi: 10.1172/JCI19603. J Clin Invest. 2004. PMID: 15520863 Free PMC article.

3

Profibrotic TGFβ responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases.

Andrianifahanana M, Wilkes MC, Gupta SK, Rahimi RA, Repellin CE, Edens M, Wittenberger J, Yin X, Maidl E, Becker J, Leof EB. Andrianifahanana M, et al. Among authors: leof eb. FASEB J. 2013 Nov;27(11):4444-54. doi: 10.1096/fj.12-224907. Epub 2013 Aug 2. FASEB J. 2013. PMID: 23913859 Free PMC article.

4

Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function.

Semela D, Das A, Langer D, Kang N, Leof E, Shah V. Semela D, et al. Gastroenterology. 2008 Aug;135(2):671-9. doi: 10.1053/j.gastro.2008.04.010. Epub 2008 Apr 16. Gastroenterology. 2008. PMID: 18570897 Free PMC article.

5

Imatinib mesylate causes genome-wide transcriptional changes in systemic sclerosis fibroblasts in vitro.

Hinchcliff M, Huang CC, Ishida W, Fang F, Lee J, Jafari N, Wilkes M, Bhattacharyya S, Leof E, Varga J. Hinchcliff M, et al. Clin Exp Rheumatol. 2012 Mar-Apr;30(2 Suppl 71):S86-96. Epub 2012 May 29. Clin Exp Rheumatol. 2012. PMID: 22691216 Free PMC article.

6

A non-Smad mechanism of fibroblast activation by transforming growth factor-beta via c-Abl and Egr-1: selective modulation by imatinib mesylate.

Bhattacharyya S, Ishida W, Wu M, Wilkes M, Mori Y, Hinchcliff M, Leof E, Varga J. Bhattacharyya S, et al. Oncogene. 2009 Mar 12;28(10):1285-97. doi: 10.1038/onc.2008.479. Epub 2009 Jan 19. Oncogene. 2009. PMID: 19151753 Free PMC article.

7

Erbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta.

Wilkes MC, Repellin CE, Hong M, Bracamonte M, Penheiter SG, Borg JP, Leof EB. Wilkes MC, et al. Among authors: leof eb. Dev Cell. 2009 Mar;16(3):433-44. doi: 10.1016/j.devcel.2009.01.009. Dev Cell. 2009. PMID: 19289088 Free PMC article.

8

Phase I trial of sirolimus combined with radiation and cisplatin in non-small cell lung cancer.

Sarkaria JN, Schwingler P, Schild SE, Grogan PT, Mladek AC, Mandrekar SJ, Tan AD, Kobayashi T, Marks RS, Kita H, Miller RC, Limper AH, Leof EB. Sarkaria JN, et al. Among authors: leof eb. J Thorac Oncol. 2007 Aug;2(8):751-7. doi: 10.1097/JTO.0b013e3180cc2587. J Thorac Oncol. 2007. PMID: 17762343 Free article. Clinical Trial.

9

Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo.

Wang S, Wilkes MC, Leof EB, Hirschberg R. Wang S, et al. Among authors: leof eb. FASEB J. 2005 Jan;19(1):1-11. doi: 10.1096/fj.04-2370com. FASEB J. 2005. PMID: 15629889

10

ERBB receptor activation is required for profibrotic responses to transforming growth factor beta.

Andrianifahanana M, Wilkes MC, Repellin CE, Edens M, Kottom TJ, Rahimi RA, Leof EB. Andrianifahanana M, et al. Among authors: leof eb. Cancer Res. 2010 Oct 1;70(19):7421-30. doi: 10.1158/0008-5472.CAN-10-0232. Epub 2010 Sep 14. Cancer Res. 2010. PMID: 20841477 Free PMC article.

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