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Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bleicher L, Aparicio R, Nunes FM, Martinez L, Gomes Dias SM, Figueira AC, Santos MA, Venturelli WH, da Silva R, Donate PM, Neves FA, Simeoni LA, Baxter JD, Webb P, Skaf MS, Polikarpov I. Bleicher L, et al. BMC Struct Biol. 2008 Jan 31;8:8. doi: 10.1186/1472-6807-8-8. BMC Struct Biol. 2008. PMID: 18237438 Free PMC article.
Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
Nascimento AS, Dias SM, Nunes FM, Aparício R, Ambrosio AL, Bleicher L, Figueira AC, Santos MA, de Oliveira Neto M, Fischer H, Togashi M, Craievich AF, Garratt RC, Baxter JD, Webb P, Polikarpov I. Nascimento AS, et al. Among authors: bleicher l. J Mol Biol. 2006 Jul 14;360(3):586-98. doi: 10.1016/j.jmb.2006.05.008. Epub 2006 May 19. J Mol Biol. 2006. PMID: 16781732
Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface.
Calgaro MR, Neto Mde O, Figueira AC, Santos MA, Portugal RV, Guzzi CA, Saidemberg DM, Bleicher L, Vernal J, Fernandez P, Terenzi H, Palma MS, Polikarpov I. Calgaro MR, et al. Among authors: bleicher l. Protein Sci. 2007 Aug;16(8):1762-72. doi: 10.1110/ps.062692207. Epub 2007 Jun 28. Protein Sci. 2007. PMID: 17600153 Free PMC article.
Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22.
de Moura PR, Watanabe L, Bleicher L, Colau D, Dumoutier L, Lemaire MM, Renauld JC, Polikarpov I. de Moura PR, et al. Among authors: bleicher l. FEBS Lett. 2009 Apr 2;583(7):1072-7. doi: 10.1016/j.febslet.2009.03.006. Epub 2009 Mar 11. FEBS Lett. 2009. PMID: 19285080 Free article.
Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I. Trivella DB, et al. Among authors: bleicher l. J Struct Biol. 2010 Jun;170(3):522-31. doi: 10.1016/j.jsb.2010.03.002. Epub 2010 Mar 6. J Struct Biol. 2010. PMID: 20211733 Free article.
58 results