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Page 1
Re: UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters.
Ichikawa W, Araki K, Fujita K, Yamamoto W, Endo H, Nagashima F, Tanaka R, Miya T, Kodama K, Sunakawa Y, Narabayashi M, Ando Y, Akiyama Y, Kawara K, Sasaki Y. Ichikawa W, et al. Among authors: kawara k. J Natl Cancer Inst. 2008 Feb 6;100(3):224-5; author reply 225. doi: 10.1093/jnci/djm302. Epub 2008 Jan 29. J Natl Cancer Inst. 2008. PMID: 18230796 No abstract available.
Genetic testing for UGT1A1*28 and *6 in Japanese patients who receive irinotecan chemotherapy.
Akiyama Y, Fujita K, Nagashima F, Yamamoto W, Endo H, Sunakawa Y, Yamashita K, Ishida H, Mizuno K, Araki K, Ichikawa W, Miya T, Narabayashi M, Kawara K, Sugiyama M, Hirose T, Ando Y, Sasaki Y. Akiyama Y, et al. Among authors: kawara k. Ann Oncol. 2008 Dec;19(12):2089-90. doi: 10.1093/annonc/mdn645. Epub 2008 Oct 26. Ann Oncol. 2008. PMID: 18953066 Free PMC article. No abstract available.
A phase I study of infusional 5-fluorouracil, leucovorin, oxaliplatin and irinotecan in Japanese patients with advanced colorectal cancer who harbor UGT1A1*1/*1,*1/*6 or *1/*28.
Sunakawa Y, Fujita K, Ichikawa W, Ishida H, Yamashita K, Araki K, Miwa K, Kawara K, Akiyama Y, Yamamoto W, Nagashima F, Saji S, Sasaki Y. Sunakawa Y, et al. Among authors: kawara k. Oncology. 2012;82(4):242-8. doi: 10.1159/000337225. Epub 2012 Apr 12. Oncology. 2012. PMID: 22508373 Clinical Trial.
Association of ATP-binding cassette, sub-family C, number 2 (ABCC2) genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with irinotecan plus infusional 5-fluorouracil/leucovorin (FOLFIRI).
Fujita K, Nagashima F, Yamamoto W, Endo H, Sunakawa Y, Yamashita K, Ishida H, Mizuno K, Matsunaga M, Araki K, Tanaka R, Ichikawa W, Miya T, Narabayashi M, Akiyama Y, Kawara K, Ando Y, Sasaki Y. Fujita K, et al. Among authors: kawara k. Biol Pharm Bull. 2008 Nov;31(11):2137-42. doi: 10.1248/bpb.31.2137. Biol Pharm Bull. 2008. PMID: 18981587 Free article. Clinical Trial.
UGT1A1*1/*28 and *1/*6 genotypes have no effects on the efficacy and toxicity of FOLFIRI in Japanese patients with advanced colorectal cancer.
Sunakawa Y, Ichikawa W, Fujita K, Nagashima F, Ishida H, Yamashita K, Mizuno K, Miwa K, Kawara K, Akiyama Y, Araki K, Yamamoto W, Miya T, Narabayashi M, Ando Y, Hirose T, Saji S, Sasaki Y. Sunakawa Y, et al. Among authors: kawara k. Cancer Chemother Pharmacol. 2011 Aug;68(2):279-84. doi: 10.1007/s00280-010-1485-8. Epub 2010 Oct 19. Cancer Chemother Pharmacol. 2011. PMID: 20957480
Phase I/II study of FOLFIRI in Japanese patients with advanced colorectal cancer.
Yamashita K, Nagashima F, Fujita K, Yamamoto W, Endo H, Miya T, Narabayashi M, Kawara K, Akiyama Y, Ando Y, Ando M, Sasaki Y. Yamashita K, et al. Among authors: kawara k. Jpn J Clin Oncol. 2011 Feb;41(2):204-9. doi: 10.1093/jjco/hyq197. Epub 2010 Oct 21. Jpn J Clin Oncol. 2011. PMID: 20965940 Clinical Trial.
Delayed elimination of SN-38 in cancer patients with severe renal failure.
Fujita K, Sunakawa Y, Miwa K, Akiyama Y, Sugiyama M, Kawara K, Ishida H, Yamashita K, Mizuno K, Saji S, Ichikawa W, Yamamoto W, Nagashima F, Miya T, Narabayashi M, Ando Y, Hirose T, Sasaki Y. Fujita K, et al. Among authors: kawara k. Drug Metab Dispos. 2011 Feb;39(2):161-4. doi: 10.1124/dmd.110.035451. Epub 2010 Oct 27. Drug Metab Dispos. 2011. PMID: 20980446 Clinical Trial.
CYP2A6 and the plasma level of 5-chloro-2, 4-dihydroxypyridine are determinants of the pharmacokinetic variability of tegafur and 5-fluorouracil, respectively, in Japanese patients with cancer given S-1.
Fujita K, Yamamoto W, Endo S, Endo H, Nagashima F, Ichikawa W, Tanaka R, Miya T, Araki K, Kodama K, Sunakawa Y, Narabayashi M, Miwa K, Ando Y, Akiyama Y, Kawara K, Kamataki T, Sasaki Y. Fujita K, et al. Among authors: kawara k. Cancer Sci. 2008 May;99(5):1049-54. doi: 10.1111/j.1349-7006.2008.00773.x. Cancer Sci. 2008. PMID: 18380793 Free PMC article. Clinical Trial.
25 results