Inglese J - Search Results

1

Quantitative high-throughput screening using a live-cell cAMP assay identifies small-molecule agonists of the TSH receptor.

Titus S, Neumann S, Zheng W, Southall N, Michael S, Klumpp C, Yasgar A, Shinn P, Thomas CJ, Inglese J, Gershengorn MC, Austin CP. Titus S, et al. Among authors: inglese j. J Biomol Screen. 2008 Feb;13(2):120-7. doi: 10.1177/1087057107313786. Epub 2008 Jan 23. J Biomol Screen. 2008. PMID: 18216391 Free PMC article.

2

A collaborative screening program for the discovery of inhibitors of HCV NS2/3 cis-cleaving protease activity.

Whitney M, Stack JH, Darke PL, Zheng W, Terzo J, Inglese J, Strulovici B, Kuo LC, Pollock BA. Whitney M, et al. Among authors: inglese j. J Biomol Screen. 2002 Apr;7(2):149-54. doi: 10.1177/108705710200700208. J Biomol Screen. 2002. PMID: 12026885

3

A 1536-well cAMP assay for Gs- and Gi-coupled receptors using enzyme fragmentation complementation.

Weber M, Ferrer M, Zheng W, Inglese J, Strulovici B, Kunapuli P. Weber M, et al. Among authors: inglese j. Assay Drug Dev Technol. 2004 Feb;2(1):39-49. doi: 10.1089/154065804322966306. Assay Drug Dev Technol. 2004. PMID: 15090209

4

Miniaturization of whole live cell-based GPCR assays using microdispensing and detection systems.

Kornienko O, Lacson R, Kunapuli P, Schneeweis J, Hoffman I, Smith T, Alberts M, Inglese J, Strulovici B. Kornienko O, et al. Among authors: inglese j. J Biomol Screen. 2004 Apr;9(3):186-95. doi: 10.1177/1087057103260070. J Biomol Screen. 2004. PMID: 15140380

5

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP. Inglese J, et al. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. doi: 10.1073/pnas.0604348103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864780 Free PMC article.

6

Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format.

Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J. Auld DS, et al. Among authors: inglese j. Methods Enzymol. 2006;414:566-89. doi: 10.1016/S0076-6879(06)14029-X. Methods Enzymol. 2006. PMID: 17110211

7

A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor.

Davis RE, Zhang YQ, Southall N, Staudt LM, Austin CP, Inglese J, Auld DS. Davis RE, et al. Among authors: inglese j. Assay Drug Dev Technol. 2007 Feb;5(1):85-103. doi: 10.1089/adt.2006.048. Assay Drug Dev Technol. 2007. PMID: 17355202

8

A high-throughput screen for aggregation-based inhibition in a large compound library.

Feng BY, Simeonov A, Jadhav A, Babaoglu K, Inglese J, Shoichet BK, Austin CP. Feng BY, et al. Among authors: inglese j. J Med Chem. 2007 May 17;50(10):2385-90. doi: 10.1021/jm061317y. Epub 2007 Apr 21. J Med Chem. 2007. PMID: 17447748

9

Reporting data from high-throughput screening of small-molecule libraries.

Inglese J, Shamu CE, Guy RK. Inglese J, et al. Nat Chem Biol. 2007 Aug;3(8):438-41. doi: 10.1038/nchembio0807-438. Nat Chem Biol. 2007. PMID: 17637769

10

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. Inglese J, et al. Nat Chem Biol. 2007 Aug;3(8):466-79. doi: 10.1038/nchembio.2007.17. Nat Chem Biol. 2007. PMID: 17637779 Review.

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