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DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours.
Plöckinger U, Hoffmann U, Geese M, Lupp A, Buchfelder M, Flitsch J, Vajkoczy P, Jakob W, Saeger W, Schulz S, Dohrmann C. Plöckinger U, et al. Among authors: saeger w. Eur J Endocrinol. 2012 Feb;166(2):223-34. doi: 10.1530/EJE-11-0737. Epub 2011 Nov 7. Eur J Endocrinol. 2012. PMID: 22065857
Preoperative octreotide treatment of growth hormone-secreting and clinically nonfunctioning pituitary macroadenomas: effect on tumor volume and lack of correlation with immunohistochemistry and somatostatin receptor scintigraphy.
Plöckinger U, Reichel M, Fett U, Saeger W, Quabbe HJ. Plöckinger U, et al. Among authors: saeger w. J Clin Endocrinol Metab. 1994 Nov;79(5):1416-23. doi: 10.1210/jcem.79.5.7962337. J Clin Endocrinol Metab. 1994. PMID: 7962337
Bevacizumab in Aggressive Pituitary Adenomas - Experience with 3 Patients.
Osterhage K, Rotermund R, Droste M, Dierlamm J, Saeger W, Petersenn S, Aberle J, Flitsch J. Osterhage K, et al. Among authors: saeger w. Exp Clin Endocrinol Diabetes. 2021 Mar;129(3):178-185. doi: 10.1055/a-1260-3975. Epub 2020 Dec 7. Exp Clin Endocrinol Diabetes. 2021. PMID: 33285600
Impact of USP8 Gene Mutations on Protein Deregulation in Cushing Disease.
Weigand I, Knobloch L, Flitsch J, Saeger W, Monoranu CM, Höfner K, Herterich S, Rotermund R, Ronchi CL, Buchfelder M, Glatzel M, Hagel C, Fassnacht M, Deutschbein T, Sbiera S. Weigand I, et al. Among authors: saeger w. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2535-2546. doi: 10.1210/jc.2018-02564. J Clin Endocrinol Metab. 2019. PMID: 30844069
346 results