Mangelsdorf DJ - Search Results

1

Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype.

Wang H, Zhang Y, Yehuda-Shnaidman E, Medvedev AV, Kumar N, Daniel KW, Robidoux J, Czech MP, Mangelsdorf DJ, Collins S. Wang H, et al. Among authors: mangelsdorf dj. Mol Cell Biol. 2008 Apr;28(7):2187-200. doi: 10.1128/MCB.01479-07. Epub 2008 Jan 14. Mol Cell Biol. 2008. PMID: 18195045 Free PMC article.

2

LuXuRies of lipid homeostasis: the unity of nuclear hormone receptors, transcription regulation, and cholesterol sensing.

Zhang Y, Mangelsdorf DJ. Zhang Y, et al. Among authors: mangelsdorf dj. Mol Interv. 2002 Apr;2(2):78-87. doi: 10.1124/mi.2.2.78. Mol Interv. 2002. PMID: 14993353 Review.

3

The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions.

Laffitte BA, Joseph SB, Chen M, Castrillo A, Repa J, Wilpitz D, Mangelsdorf D, Tontonoz P. Laffitte BA, et al. Mol Cell Biol. 2003 Mar;23(6):2182-91. doi: 10.1128/MCB.23.6.2182-2191.2003. Mol Cell Biol. 2003. PMID: 12612088 Free PMC article.

4

Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo.

Kir S, Zhang Y, Gerard RD, Kliewer SA, Mangelsdorf DJ. Kir S, et al. Among authors: mangelsdorf dj. J Biol Chem. 2012 Nov 30;287(49):41334-41. doi: 10.1074/jbc.M112.421834. Epub 2012 Oct 4. J Biol Chem. 2012. PMID: 23038264 Free PMC article.

5

Identification of a liver-specific uridine phosphorylase that is regulated by multiple lipid-sensing nuclear receptors.

Zhang Y, Repa JJ, Inoue Y, Hayhurst GP, Gonzalez FJ, Mangelsdorf DJ. Zhang Y, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2004 Apr;18(4):851-62. doi: 10.1210/me.2003-0285. Epub 2004 Jan 8. Mol Endocrinol. 2004. PMID: 14715930

6

Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

Zhang Y, Repa JJ, Gauthier K, Mangelsdorf DJ. Zhang Y, et al. Among authors: mangelsdorf dj. J Biol Chem. 2001 Nov 16;276(46):43018-24. doi: 10.1074/jbc.M107823200. Epub 2001 Sep 18. J Biol Chem. 2001. PMID: 11562371 Free article.

7

Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands.

Yang C, McDonald JG, Patel A, Zhang Y, Umetani M, Xu F, Westover EJ, Covey DF, Mangelsdorf DJ, Cohen JC, Hobbs HH. Yang C, et al. Among authors: mangelsdorf dj. J Biol Chem. 2006 Sep 22;281(38):27816-26. doi: 10.1074/jbc.M603781200. Epub 2006 Jul 20. J Biol Chem. 2006. PMID: 16857673 Free article.

8

LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.

Patel R, Patel M, Tsai R, Lin V, Bookout AL, Zhang Y, Magomedova L, Li T, Chan JF, Budd C, Mangelsdorf DJ, Cummins CL. Patel R, et al. Among authors: mangelsdorf dj. J Clin Invest. 2011 Jan;121(1):431-41. doi: 10.1172/JCI41681. Epub 2010 Dec 1. J Clin Invest. 2011. PMID: 21123945 Free PMC article.

9

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.

Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA. Lee YK, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2008 Jun;22(6):1345-56. doi: 10.1210/me.2007-0565. Epub 2008 Mar 6. Mol Endocrinol. 2008. PMID: 18323469 Free PMC article.

10

Liver X receptors regulate adrenal cholesterol balance.

Cummins CL, Volle DH, Zhang Y, McDonald JG, Sion B, Lefrançois-Martinez AM, Caira F, Veyssière G, Mangelsdorf DJ, Lobaccaro JM. Cummins CL, et al. Among authors: mangelsdorf dj. J Clin Invest. 2006 Jul;116(7):1902-12. doi: 10.1172/JCI28400. J Clin Invest. 2006. PMID: 16823488 Free PMC article.

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