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The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells.
Chancellor A, Constantin D, Giuliano Berloffa, Yang Q, Nosi V, Loureiro JP, Colombo R, Jakob RP, Joss D, Pfeffer M, De Simone G, Morabito A, Schaefer V, Vacchini A, Brunelli L, Montagna D, Heim M, Zippelius A, Davoli E, Häussinger D, Maier T, Mori L, De Libero G. Chancellor A, et al. Among authors: haussinger d. Immunity. 2024 Dec 11:S1074-7613(24)00534-X. doi: 10.1016/j.immuni.2024.11.019. Online ahead of print. Immunity. 2024. PMID: 39701104 Free article.
Toward Molecular Textiles: Synthesis and Characterization of Molecular Patches.
Kroonen CCE, Hinaut A, D'Addio A, Prescimone A, Häussinger D, Navarro-Marín G, Fuhr O, Fenske D, Meyer E, Mayor M. Kroonen CCE, et al. Among authors: haussinger d. Chemistry. 2024 Dec 10;30(69):e202402866. doi: 10.1002/chem.202402866. Epub 2024 Nov 5. Chemistry. 2024. PMID: 39325654 Free PMC article.
Nucleobase adducts bind MR1 and stimulate MR1-restricted T cells.
Vacchini A, Chancellor A, Yang Q, Colombo R, Spagnuolo J, Berloffa G, Joss D, Øyås O, Lecchi C, De Simone G, Beshirova A, Nosi V, Loureiro JP, Morabito A, De Gregorio C, Pfeffer M, Schaefer V, Prota G, Zippelius A, Stelling J, Häussinger D, Brunelli L, Villalta P, Lepore M, Davoli E, Balbo S, Mori L, De Libero G. Vacchini A, et al. Among authors: haussinger d. Sci Immunol. 2024 May 10;9(95):eadn0126. doi: 10.1126/sciimmunol.adn0126. Epub 2024 May 10. Sci Immunol. 2024. PMID: 38728413
Catalyst control over pentavalent stereocentres.
Budeev A, Dong J, Häussinger D, Sparr C. Budeev A, et al. Among authors: haussinger d. Nat Commun. 2023 Dec 4;14(1):8013. doi: 10.1038/s41467-023-43750-w. Nat Commun. 2023. PMID: 38049395 Free PMC article.
HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.
Zecher BF, Ellinghaus D, Schloer S, Niehrs A, Padoan B, Baumdick ME, Yuki Y, Martin MP, Glow D, Schröder-Schwarz J, Niersch J, Brias S, Müller LM, Habermann R, Kretschmer P, Früh T, Dänekas J, Wehmeyer MH, Poch T, Sebode M; International PSC Study Group (IPSCSG); Ellinghaus E, Degenhardt F, Körner C, Hoelzemer A, Fehse B, Oldhafer KJ, Schumacher U, Sauter G, Carrington M, Franke A, Bunders MJ, Schramm C, Altfeld M. Zecher BF, et al. Gut. 2024 Jan 5;73(2):325-337. doi: 10.1136/gutjnl-2023-329524. Gut. 2024. PMID: 37788895 Free PMC article.
1,112 results