Willingham MC - Search Results

1

GMP production and characterization of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1) for phase I/II clinical trials.

Woo JH, Liu JS, Kang SH, Singh R, Park SK, Su Y, Ortiz J, Neville DM Jr, Willingham MC, Frankel AE. Woo JH, et al. Among authors: willingham mc. Protein Expr Purif. 2008 Mar;58(1):1-11. doi: 10.1016/j.pep.2007.11.006. Epub 2007 Nov 22. Protein Expr Purif. 2008. PMID: 18160309

2

Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.

Urieto JO, Liu T, Black JH, Cohen KA, Hall PD, Willingham MC, Pennell LK, Hogge DE, Kreitman RJ, Frankel AE. Urieto JO, et al. Among authors: willingham mc. Protein Expr Purif. 2004 Jan;33(1):123-33. doi: 10.1016/j.pep.2003.09.003. Protein Expr Purif. 2004. PMID: 14680969

3

High-level expression and purification of the recombinant diphtheria fusion toxin DTGM for PHASE I clinical trials.

Frankel AE, Ramage J, Latimer A, Feely T, Delatte S, Hall P, Tagge E, Kreitman R, Willingham M. Frankel AE, et al. Protein Expr Purif. 1999 Jun;16(1):190-201. doi: 10.1006/prep.1999.1071. Protein Expr Purif. 1999. PMID: 10336877 Clinical Trial.

4

Clinical trials of targeted toxins.

Frankel AE, Tagge EP, Willingham MC. Frankel AE, et al. Among authors: willingham mc. Semin Cancer Biol. 1995 Oct;6(5):307-17. doi: 10.1006/scbi.1995.0039. Semin Cancer Biol. 1995. PMID: 8562908 Review.

5

Preproricin expressed in Nicotiana tabacum cells in vitro is fully processed and biologically active.

Tagge EP, Chandler J, Harris B, Czako M, Marton L, Willingham MC, Burbage C, Afrin L, Frankel AE. Tagge EP, et al. Among authors: willingham mc. Protein Expr Purif. 1996 Aug;8(1):109-18. doi: 10.1006/prep.1996.0080. Protein Expr Purif. 1996. PMID: 8812841

6

A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells.

Liu TF, Cohen KA, Ramage JG, Willingham MC, Thorburn AM, Frankel AE. Liu TF, et al. Among authors: willingham mc. Cancer Res. 2003 Apr 15;63(8):1834-7. Cancer Res. 2003. PMID: 12702570

7

Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage.

Kuo SR, Willingham MC, Bour SH, Andreas EA, Park SK, Jackson C, Duesbery NS, Leppla SH, Tang WJ, Frankel AE. Kuo SR, et al. Among authors: willingham mc. Microb Pathog. 2008 Jun;44(6):467-72. doi: 10.1016/j.micpath.2007.12.001. Epub 2007 Dec 23. Microb Pathog. 2008. PMID: 18222626

8

Characterization of a ricin fusion toxin targeted to the interleukin-2 receptor.

Frankel AE, Burbage C, Fu T, Tagge E, Chandler J, Willingham M. Frankel AE, et al. Protein Eng. 1996 Oct;9(10):913-9. doi: 10.1093/protein/9.10.913. Protein Eng. 1996. PMID: 8931131

9

Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice.

Hall PD, Kreitman RJ, Willingham MC, Frankel AE. Hall PD, et al. Among authors: willingham mc. Toxicol Appl Pharmacol. 1998 May;150(1):91-7. doi: 10.1006/taap.1998.8389. Toxicol Appl Pharmacol. 1998. PMID: 9630457

10

Diphtheria toxin-epidermal growth factor fusion protein and Pseudomonas exotoxin-interleukin 13 fusion protein exert synergistic toxicity against human glioblastoma multiforme cells.

Liu TF, Willingham MC, Tatter SB, Cohen KA, Lowe AC, Thorburn A, Frankel AE. Liu TF, et al. Among authors: willingham mc. Bioconjug Chem. 2003 Nov-Dec;14(6):1107-14. doi: 10.1021/bc034111+. Bioconjug Chem. 2003. PMID: 14624623

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