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Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver.
Elmén J, Lindow M, Silahtaroglu A, Bak M, Christensen M, Lind-Thomsen A, Hedtjärn M, Hansen JB, Hansen HF, Straarup EM, McCullagh K, Kearney P, Kauppinen S. Elmén J, et al. Among authors: hansen jb, hansen hf. Nucleic Acids Res. 2008 Mar;36(4):1153-62. doi: 10.1093/nar/gkm1113. Epub 2007 Dec 23. Nucleic Acids Res. 2008. PMID: 18158304 Free PMC article.
SPC3042: a proapoptotic survivin inhibitor.
Hansen JB, Fisker N, Westergaard M, Kjaerulff LS, Hansen HF, Thrue CA, Rosenbohm C, Wissenbach M, Orum H, Koch T. Hansen JB, et al. Among authors: hansen hf. Mol Cancer Ther. 2008 Sep;7(9):2736-45. doi: 10.1158/1535-7163.MCT-08-0161. Mol Cancer Ther. 2008. PMID: 18790754 Free article.
Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents.
Stein CA, Hansen JB, Lai J, Wu S, Voskresenskiy A, Høg A, Worm J, Hedtjärn M, Souleimanian N, Miller P, Soifer HS, Castanotto D, Benimetskaya L, Ørum H, Koch T. Stein CA, et al. Among authors: hansen jb. Nucleic Acids Res. 2010 Jan;38(1):e3. doi: 10.1093/nar/gkp841. Epub 2009 Oct 23. Nucleic Acids Res. 2010. PMID: 19854938 Free PMC article.
Synthesis and biological evaluation of LNA phosphoramidates.
Jensen J, Sjøgren G, Hansen JB, Rosenbohm C, Koch T. Jensen J, et al. Among authors: hansen jb. Nucleosides Nucleotides Nucleic Acids. 2008 Jan;27(1):37-42. doi: 10.1080/15257770701571834. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18188768
Antisense knockdown of PKC-alpha using LNA-oligos.
Hansen JB, Westergaard M, Thrue CA, Giwercman B, Oerum H. Hansen JB, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1607-9. doi: 10.1081/ncn-120023045. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565477
901 results