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The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists.
Netea MG, Ferwerda G, de Jong DJ, Werts C, Boneca IG, Jéhanno M, Van Der Meer JW, Mengin-Lecreulx D, Sansonetti PJ, Philpott DJ, Dharancy S, Girardin SE. Netea MG, et al. Among authors: girardin se. J Biol Chem. 2005 Oct 28;280(43):35859-67. doi: 10.1074/jbc.M504924200. Epub 2005 Aug 22. J Biol Chem. 2005. PMID: 16115863 Free article.
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
Netea MG, Azam T, Ferwerda G, Girardin SE, Walsh M, Park JS, Abraham E, Kim JM, Yoon DY, Dinarello CA, Kim SH. Netea MG, et al. Among authors: girardin se. Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16309-14. doi: 10.1073/pnas.0508237102. Epub 2005 Oct 31. Proc Natl Acad Sci U S A. 2005. PMID: 16260731 Free PMC article.
Normal responses to specific NOD1 ligands.
Ferwerda G, Girardin SE, van der Meer JW, Netea MG. Ferwerda G, et al. Among authors: girardin se. Eur J Immunol. 2006 Oct;36(10):2817-8; author reply 2818. doi: 10.1002/eji.200636332. Eur J Immunol. 2006. PMID: 17013977 Free article. No abstract available.
189 results