Murphy MP - Search Results

1

Safety, tolerability, pharmacokinetics, and Abeta levels after short-term administration of R-flurbiprofen in healthy elderly individuals.

Galasko DR, Graff-Radford N, May S, Hendrix S, Cottrell BA, Sagi SA, Mather G, Laughlin M, Zavitz KH, Swabb E, Golde TE, Murphy MP, Koo EH. Galasko DR, et al. Among authors: murphy mp. Alzheimer Dis Assoc Disord. 2007 Oct-Dec;21(4):292-9. doi: 10.1097/WAD.0b013e31815d1048. Alzheimer Dis Assoc Disord. 2007. PMID: 18090435 Clinical Trial.

2

Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.

Kukar T, Prescott S, Eriksen JL, Holloway V, Murphy MP, Koo EH, Golde TE, Nicolle MM. Kukar T, et al. Among authors: murphy mp. BMC Neurosci. 2007 Jul 24;8:54. doi: 10.1186/1471-2202-8-54. BMC Neurosci. 2007. PMID: 17650315 Free PMC article.

3

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.

Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. Weggen S, et al. Among authors: murphy mp. Nature. 2001 Nov 8;414(6860):212-6. doi: 10.1038/35102591. Nature. 2001. PMID: 11700559

4

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production.

Kukar T, Murphy MP, Eriksen JL, Sagi SA, Weggen S, Smith TE, Ladd T, Khan MA, Kache R, Beard J, Dodson M, Merit S, Ozols VV, Anastasiadis PZ, Das P, Fauq A, Koo EH, Golde TE. Kukar T, et al. Among authors: murphy mp. Nat Med. 2005 May;11(5):545-50. doi: 10.1038/nm1235. Epub 2005 Apr 17. Nat Med. 2005. PMID: 15834426

5

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.

Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Oddo S, et al. Among authors: murphy mp. Neuron. 2003 Jul 31;39(3):409-21. doi: 10.1016/s0896-6273(03)00434-3. Neuron. 2003. PMID: 12895417 Free article.

6

Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition.

Das P, Murphy MP, Younkin LH, Younkin SG, Golde TE. Das P, et al. Among authors: murphy mp. Neurobiol Aging. 2001 Sep-Oct;22(5):721-7. doi: 10.1016/s0197-4580(01)00245-7. Neurobiol Aging. 2001. PMID: 11705631

7

Androgens modulate beta-amyloid levels in male rat brain.

Ramsden M, Nyborg AC, Murphy MP, Chang L, Stanczyk FZ, Golde TE, Pike CJ. Ramsden M, et al. Among authors: murphy mp. J Neurochem. 2003 Nov;87(4):1052-5. doi: 10.1046/j.1471-4159.2003.02114.x. J Neurochem. 2003. PMID: 14622134 Free article.

8

Inclusion-body myositis and Alzheimer disease: two sides of the same coin, or different currencies altogether?

Murphy MP, Golde TE. Murphy MP, et al. Neurology. 2006 Jan 24;66(2 Suppl 1):S65-8. doi: 10.1212/01.wnl.0000192108.02654.ac. Neurology. 2006. PMID: 16432148 Review. No abstract available.

9

Inclusion body myositis-like phenotype induced by transgenic overexpression of beta APP in skeletal muscle.

Sugarman MC, Yamasaki TR, Oddo S, Echegoyen JC, Murphy MP, Golde TE, Jannatipour M, Leissring MA, LaFerla FM. Sugarman MC, et al. Among authors: murphy mp. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6334-9. doi: 10.1073/pnas.082545599. Epub 2002 Apr 23. Proc Natl Acad Sci U S A. 2002. PMID: 11972038 Free PMC article.

10

FAD-linked mutations in presenilin 1 alter the length of Abeta peptides derived from betaAPP transmembrane domain mutants.

Murphy MP, Uljon SN, Golde TE, Wang R. Murphy MP, et al. Biochim Biophys Acta. 2002 Mar 16;1586(2):199-209. doi: 10.1016/s0925-4439(01)00098-9. Biochim Biophys Acta. 2002. PMID: 11959461 Free article.

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