Dean M - Search Results

1

New inhibitors of ABCG2 identified by high-throughput screening.

Henrich CJ, Robey RW, Bokesch HR, Bates SE, Shukla S, Ambudkar SV, Dean M, McMahon JB. Henrich CJ, et al. Among authors: dean m. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3271-8. doi: 10.1158/1535-7163.MCT-07-0352. Mol Cancer Ther. 2007. PMID: 18089721 Free PMC article.

2

A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance.

Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V, Dean M. Allikmets R, et al. Among authors: dean m. Cancer Res. 1998 Dec 1;58(23):5337-9. Cancer Res. 1998. PMID: 9850061

3

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes.

Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Cristensen B, Brangi M, Greenberger L, Dean M, Fojo T, Bates SE. Miyake K, et al. Among authors: dean m. Cancer Res. 1999 Jan 1;59(1):8-13. Cancer Res. 1999. PMID: 9892175

4

Amplification of 4q21-q22 and the MXR gene in independently derived mitoxantrone-resistant cell lines.

Knutsen T, Rao VK, Ried T, Mickley L, Schneider E, Miyake K, Ghadimi BM, Padilla-Nash H, Pack S, Greenberger L, Cowan K, Dean M, Fojo T, Bates S. Knutsen T, et al. Among authors: dean m. Genes Chromosomes Cancer. 2000 Jan;27(1):110-6. Genes Chromosomes Cancer. 2000. PMID: 10564593

5

An ATP-binding cassette gene (ABCG3) closely related to the multidrug transporter ABCG2 (MXR/ABCP) has an unusual ATP-binding domain.

Mickley L, Jain P, Miyake K, Schriml LM, Rao K, Fojo T, Bates S, Dean M. Mickley L, et al. Among authors: dean m. Mamm Genome. 2001 Jan;12(1):86-8. doi: 10.1007/s003350010237. Mamm Genome. 2001. PMID: 11178751 No abstract available.

6

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

Honjo Y, Hrycyna CA, Yan QW, Medina-Pérez WY, Robey RW, van de Laar A, Litman T, Dean M, Bates SE. Honjo Y, et al. Among authors: dean m. Cancer Res. 2001 Sep 15;61(18):6635-9. Cancer Res. 2001. PMID: 11559526

7

Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1).

Honjo Y, Morisaki K, Huff LM, Robey RW, Hung J, Dean M, Bates SE. Honjo Y, et al. Among authors: dean m. Cancer Biol Ther. 2002 Nov-Dec;1(6):696-702. doi: 10.4161/cbt.322. Cancer Biol Ther. 2002. PMID: 12642696 Free article.

8

Mutational analysis of ABCG2: role of the GXXXG motif.

Polgar O, Robey RW, Morisaki K, Dean M, Michejda C, Sauna ZE, Ambudkar SV, Tarasova N, Bates SE. Polgar O, et al. Among authors: dean m. Biochemistry. 2004 Jul 27;43(29):9448-56. doi: 10.1021/bi0497953. Biochemistry. 2004. PMID: 15260487

9

Tumour stem cells and drug resistance.

Dean M, Fojo T, Bates S. Dean M, et al. Nat Rev Cancer. 2005 Apr;5(4):275-84. doi: 10.1038/nrc1590. Nat Rev Cancer. 2005. PMID: 15803154 Review.

10

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

Henrich CJ, Bokesch HR, Dean M, Bates SE, Robey RW, Goncharova EI, Wilson JA, McMahon JB. Henrich CJ, et al. Among authors: dean m. J Biomol Screen. 2006 Mar;11(2):176-83. doi: 10.1177/1087057105284576. Epub 2006 Feb 20. J Biomol Screen. 2006. PMID: 16490770

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