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Page 1
Mutations of the beta2-microglobulin gene result in a lack of HLA class I molecules on melanoma cells of two patients immunized with MAGE peptides.
Benitez R, Godelaine D, Lopez-Nevot MA, Brasseur F, Jiménez P, Marchand M, Oliva MR, van Baren N, Cabrera T, Andry G, Landry C, Ruiz-Cabello F, Boon T, Garrido F. Benitez R, et al. Among authors: van baren n. Tissue Antigens. 1998 Dec;52(6):520-9. doi: 10.1111/j.1399-0039.1998.tb03082.x. Tissue Antigens. 1998. PMID: 9894850
Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1.
Marchand M, van Baren N, Weynants P, Brichard V, Dréno B, Tessier MH, Rankin E, Parmiani G, Arienti F, Humblet Y, Bourlond A, Vanwijck R, Liénard D, Beauduin M, Dietrich PY, Russo V, Kerger J, Masucci G, Jäger E, De Greve J, Atzpodien J, Brasseur F, Coulie PG, van der Bruggen P, Boon T. Marchand M, et al. Among authors: van baren n, van der bruggen p. Int J Cancer. 1999 Jan 18;80(2):219-30. doi: 10.1002/(sici)1097-0215(19990118)80:2<219::aid-ijc10>3.0.co;2-s. Int J Cancer. 1999. PMID: 9935203 Clinical Trial.
Expression of gene MAGE-A4 in Reed-Sternberg cells.
Chambost H, Van Baren N, Brasseur F, Godelaine D, Xerri L, Landi SJ, Theate I, Plumas J, Spagnoli GC, Michel G, Coulie PG, Olive D. Chambost H, et al. Among authors: van baren n. Blood. 2000 Jun 1;95(11):3530-3. Blood. 2000. PMID: 10828039 Free article.
MAGE-A genes are not expressed in human leukemias.
Chambost H, van Baren N, Brasseur F, Olive D. Chambost H, et al. Among authors: van baren n. Leukemia. 2001 Nov;15(11):1769-71. doi: 10.1038/sj.leu.2402278. Leukemia. 2001. PMID: 11681419
Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma.
Kruit WH, van Ojik HH, Brichard VG, Escudier B, Dorval T, Dréno B, Patel P, van Baren N, Avril MF, Piperno S, Khammari A, Stas M, Ritter G, Lethé B, Godelaine D, Brasseur F, Zhang Y, van der Bruggen P, Boon T, Eggermont AM, Marchand M. Kruit WH, et al. Among authors: van baren n, van der bruggen p, van ojik hh. Int J Cancer. 2005 Nov 20;117(4):596-604. doi: 10.1002/ijc.21264. Int J Cancer. 2005. PMID: 15945101 Clinical Trial.
Vaccination of a melanoma patient with mature dendritic cells pulsed with MAGE-3 peptides triggers the activity of nonvaccine anti-tumor cells.
Carrasco J, Van Pel A, Neyns B, Lethé B, Brasseur F, Renkvist N, van der Bruggen P, van Baren N, Paulus R, Thielemans K, Boon T, Godelaine D. Carrasco J, et al. Among authors: van pel a, van baren n, van der bruggen p. J Immunol. 2008 Mar 1;180(5):3585-93. doi: 10.4049/jimmunol.180.5.3585. J Immunol. 2008. PMID: 18292586 Clinical Trial.
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