Lee S - Search Results

1

Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery.

Chae SY, Jin CH, Shin HJ, Youn YS, Lee S, Lee KC. Chae SY, et al. Among authors: lee kc, lee s. Bioconjug Chem. 2008 Jan;19(1):334-41. doi: 10.1021/bc700292v. Epub 2007 Dec 14. Bioconjug Chem. 2008. PMID: 18078308

2

Synthesis, characterization, and pharmacokinetic studies of PEGylated glucagon-like peptide-1.

Lee SH, Lee S, Youn YS, Na DH, Chae SY, Byun Y, Lee KC. Lee SH, et al. Among authors: lee kc, lee s. Bioconjug Chem. 2005 Mar-Apr;16(2):377-82. doi: 10.1021/bc049735+. Bioconjug Chem. 2005. PMID: 15769092

3

Evaluation of therapeutic potentials of site-specific PEGylated glucagon-like peptide-1 isomers as a type 2 anti-diabetic treatment: Insulinotropic activity, glucose-stabilizing capability, and proteolytic stability.

Youn YS, Chae SY, Lee S, Jeon JE, Shin HG, Lee KC. Youn YS, et al. Among authors: lee kc, lee s. Biochem Pharmacol. 2007 Jan 1;73(1):84-93. doi: 10.1016/j.bcp.2006.09.013. Epub 2006 Sep 17. Biochem Pharmacol. 2007. PMID: 17054919

4

Improved peroral delivery of glucagon-like peptide-1 by site-specific biotin modification: design, preparation, and biological evaluation.

Youn YS, Chae SY, Lee S, Kwon MJ, Shin HJ, Lee KC. Youn YS, et al. Among authors: lee kc, lee s. Eur J Pharm Biopharm. 2008 Mar;68(3):667-75. doi: 10.1016/j.ejpb.2007.07.009. Epub 2007 Aug 2. Eur J Pharm Biopharm. 2008. PMID: 17904340

5

Pharmacokinetic and pharmacodynamic evaluation of site-specific PEGylated glucagon-like peptide-1 analogs as flexible postprandial-glucose controllers.

Chae SY, Chun YG, Lee S, Jin CH, Lee ES, Lee KC, Youn YS. Chae SY, et al. Among authors: lee kc, lee es, lee s. J Pharm Sci. 2009 Apr;98(4):1556-67. doi: 10.1002/jps.21532. J Pharm Sci. 2009. PMID: 18704955

6

Intrapulmonary potential of polyethylene glycol-modified glucagon-like peptide-1s as a type 2 anti-diabetic agent.

Lee KC, Chae SY, Kim TH, Lee S, Lee ES, Youn YS. Lee KC, et al. Among authors: lee es, lee s. Regul Pept. 2009 Jan 8;152(1-3):101-7. doi: 10.1016/j.regpep.2008.09.008. Epub 2008 Oct 14. Regul Pept. 2009. PMID: 18951927

7

A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice.

Jin CH, Chae SY, Son S, Kim TH, Um KA, Youn YS, Lee S, Lee KC. Jin CH, et al. Among authors: lee kc, lee s. J Control Release. 2009 Feb 10;133(3):172-7. doi: 10.1016/j.jconrel.2008.09.091. Epub 2008 Oct 21. J Control Release. 2009. PMID: 18977255

8

Preparation and structural, biochemical, and pharmaceutical characterizations of bile acid-modified long-acting exendin-4 derivatives.

Son S, Chae SY, Kim CW, Choi YG, Jung SY, Lee S, Lee KC. Son S, et al. Among authors: lee kc, lee s. J Med Chem. 2009 Nov 12;52(21):6889-96. doi: 10.1021/jm901153x. J Med Chem. 2009. PMID: 19827752

9

Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs.

Chae SY, Jin CH, Shin JH, Son S, Kim TH, Lee S, Youn YS, Byun Y, Lee MS, Lee KC. Chae SY, et al. Among authors: lee ms, lee kc, lee s. J Control Release. 2010 Mar 3;142(2):206-13. doi: 10.1016/j.jconrel.2009.10.025. Epub 2009 Nov 10. J Control Release. 2010. PMID: 19900495

10

Mono-PEGylated dimeric exendin-4 as high receptor binding and long-acting conjugates for type 2 anti-diabetes therapeutics.

Kim TH, Jiang HH, Lee S, Youn YS, Park CW, Byun Y, Chen X, Lee KC. Kim TH, et al. Among authors: lee kc, lee s. Bioconjug Chem. 2011 Apr 20;22(4):625-32. doi: 10.1021/bc100404x. Epub 2011 Mar 14. Bioconjug Chem. 2011. PMID: 21401109

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