Lee KC - Search Results

1

Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery.

Chae SY, Jin CH, Shin HJ, Youn YS, Lee S, Lee KC. Chae SY, et al. Among authors: lee kc, lee s. Bioconjug Chem. 2008 Jan;19(1):334-41. doi: 10.1021/bc700292v. Epub 2007 Dec 14. Bioconjug Chem. 2008. PMID: 18078308

2

Synthesis, characterization, and pharmacokinetic studies of PEGylated glucagon-like peptide-1.

Lee SH, Lee S, Youn YS, Na DH, Chae SY, Byun Y, Lee KC. Lee SH, et al. Among authors: lee kc, lee s. Bioconjug Chem. 2005 Mar-Apr;16(2):377-82. doi: 10.1021/bc049735+. Bioconjug Chem. 2005. PMID: 15769092

3

Oral delivery of mono-PEGylated sCT (Lys18) in rats: regional difference in stability and hypocalcemic effect.

Mansoor S, Youn YS, Lee KC. Mansoor S, et al. Among authors: lee kc. Pharm Dev Technol. 2005;10(3):389-96. doi: 10.1081/pdt-65686. Pharm Dev Technol. 2005. PMID: 16176019

4

Improved intestinal delivery of salmon calcitonin by Lys18-amine specific PEGylation: stability, permeability, pharmacokinetic behavior and in vivo hypocalcemic efficacy.

Youn YS, Jung JY, Oh SH, Yoo SD, Lee KC. Youn YS, et al. Among authors: lee kc. J Control Release. 2006 Sep 12;114(3):334-42. doi: 10.1016/j.jconrel.2006.06.007. Epub 2006 Jun 14. J Control Release. 2006. PMID: 16884808

5

Evaluation of therapeutic potentials of site-specific PEGylated glucagon-like peptide-1 isomers as a type 2 anti-diabetic treatment: Insulinotropic activity, glucose-stabilizing capability, and proteolytic stability.

Youn YS, Chae SY, Lee S, Jeon JE, Shin HG, Lee KC. Youn YS, et al. Among authors: lee kc, lee s. Biochem Pharmacol. 2007 Jan 1;73(1):84-93. doi: 10.1016/j.bcp.2006.09.013. Epub 2006 Sep 17. Biochem Pharmacol. 2007. PMID: 17054919

6

Site-specific PEGylation for high-yield preparation of Lys(21)-amine PEGylated growth hormone-releasing factor (GRF) (1-29) using a GRF(1-29) derivative FMOC-protected at Tyr(1) and Lys(12).

Youn YS, Lee KC. Youn YS, et al. Among authors: lee kc. Bioconjug Chem. 2007 Mar-Apr;18(2):500-6. doi: 10.1021/bc060173z. Epub 2007 Jan 23. Bioconjug Chem. 2007. PMID: 17243755

7

Improved peroral delivery of glucagon-like peptide-1 by site-specific biotin modification: design, preparation, and biological evaluation.

Youn YS, Chae SY, Lee S, Kwon MJ, Shin HJ, Lee KC. Youn YS, et al. Among authors: lee kc, lee s. Eur J Pharm Biopharm. 2008 Mar;68(3):667-75. doi: 10.1016/j.ejpb.2007.07.009. Epub 2007 Aug 2. Eur J Pharm Biopharm. 2008. PMID: 17904340

8

Pharmacokinetic and pharmacodynamic evaluation of site-specific PEGylated glucagon-like peptide-1 analogs as flexible postprandial-glucose controllers.

Chae SY, Chun YG, Lee S, Jin CH, Lee ES, Lee KC, Youn YS. Chae SY, et al. Among authors: lee kc, lee es, lee s. J Pharm Sci. 2009 Apr;98(4):1556-67. doi: 10.1002/jps.21532. J Pharm Sci. 2009. PMID: 18704955

9

Intrapulmonary potential of polyethylene glycol-modified glucagon-like peptide-1s as a type 2 anti-diabetic agent.

Lee KC, Chae SY, Kim TH, Lee S, Lee ES, Youn YS. Lee KC, et al. Among authors: lee es, lee s. Regul Pept. 2009 Jan 8;152(1-3):101-7. doi: 10.1016/j.regpep.2008.09.008. Epub 2008 Oct 14. Regul Pept. 2009. PMID: 18951927

10

A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice.

Jin CH, Chae SY, Son S, Kim TH, Um KA, Youn YS, Lee S, Lee KC. Jin CH, et al. Among authors: lee kc, lee s. J Control Release. 2009 Feb 10;133(3):172-7. doi: 10.1016/j.jconrel.2008.09.091. Epub 2008 Oct 21. J Control Release. 2009. PMID: 18977255

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