Kannan N - Search Results

1

Evolution of allostery in the cyclic nucleotide binding module.

Kannan N, Wu J, Anand GS, Yooseph S, Neuwald AF, Venter JC, Taylor SS. Kannan N, et al. Genome Biol. 2007;8(12):R264. doi: 10.1186/gb-2007-8-12-r264. Genome Biol. 2007. PMID: 18076763 Free PMC article.

2

Ran's C-terminal, basic patch, and nucleotide exchange mechanisms in light of a canonical structure for Rab, Rho, Ras, and Ran GTPases.

Neuwald AF, Kannan N, Poleksic A, Hata N, Liu JS. Neuwald AF, et al. Among authors: kannan n. Genome Res. 2003 Apr;13(4):673-92. doi: 10.1101/gr.862303. Genome Res. 2003. PMID: 12671004 Free PMC article.

3

Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2alpha.

Kannan N, Neuwald AF. Kannan N, et al. Protein Sci. 2004 Aug;13(8):2059-77. doi: 10.1110/ps.04637904. Protein Sci. 2004. PMID: 15273306 Free PMC article.

4

Computational analysis of protein tyrosine phosphatases: practical guide to bioinformatics and data resources.

Andersen JN, Del Vecchio RL, Kannan N, Gergel J, Neuwald AF, Tonks NK. Andersen JN, et al. Among authors: kannan n. Methods. 2005 Jan;35(1):90-114. doi: 10.1016/j.ymeth.2004.07.012. Methods. 2005. PMID: 15588990 Review.

5

Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?

Kannan N, Neuwald AF. Kannan N, et al. J Mol Biol. 2005 Sep 2;351(5):956-72. doi: 10.1016/j.jmb.2005.06.057. J Mol Biol. 2005. PMID: 16051269

6

Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix.

Wu J, Yang J, Kannan N, Madhusudan, Xuong NH, Ten Eyck LF, Taylor SS. Wu J, et al. Among authors: kannan n. Protein Sci. 2005 Nov;14(11):2871-9. doi: 10.1110/ps.051715205. Protein Sci. 2005. PMID: 16253959 Free PMC article.

7

The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module.

Kannan N, Haste N, Taylor SS, Neuwald AF. Kannan N, et al. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1272-7. doi: 10.1073/pnas.0610251104. Epub 2007 Jan 16. Proc Natl Acad Sci U S A. 2007. PMID: 17227859 Free PMC article.

8

Structural and functional diversity of the microbial kinome.

Kannan N, Taylor SS, Zhai Y, Venter JC, Manning G. Kannan N, et al. PLoS Biol. 2007 Mar;5(3):e17. doi: 10.1371/journal.pbio.0050017. PLoS Biol. 2007. PMID: 17355172 Free PMC article.

9

Analogous regulatory sites within the alphaC-beta4 loop regions of ZAP-70 tyrosine kinase and AGC kinases.

Kannan N, Neuwald AF, Taylor SS. Kannan N, et al. Biochim Biophys Acta. 2008 Jan;1784(1):27-32. doi: 10.1016/j.bbapap.2007.09.007. Epub 2007 Sep 29. Biochim Biophys Acta. 2008. PMID: 17977811 Free PMC article. Review.

10

Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.

Taylor SS, Kim C, Cheng CY, Brown SH, Wu J, Kannan N. Taylor SS, et al. Among authors: kannan n. Biochim Biophys Acta. 2008 Jan;1784(1):16-26. doi: 10.1016/j.bbapap.2007.10.002. Epub 2007 Oct 12. Biochim Biophys Acta. 2008. PMID: 17996741 Free PMC article. Review.

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