Moroi M - Search Results

1

Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI.

Wijeyewickrema LC, Gardiner EE, Moroi M, Berndt MC, Andrews RK. Wijeyewickrema LC, et al. Among authors: moroi m. Thromb Haemost. 2007 Dec;98(6):1285-90. Thromb Haemost. 2007. PMID: 18064326

2

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding.

Al-Tamimi M, Mu FT, Arthur JF, Shen Y, Moroi M, Berndt MC, Andrews RK, Gardiner EE. Al-Tamimi M, et al. Among authors: moroi m. Platelets. 2009 Mar;20(2):75-82. doi: 10.1080/09537100802645029. Platelets. 2009. PMID: 19235048 Free article.

3

Measuring soluble platelet glycoprotein VI in human plasma by ELISA.

Al-Tamimi M, Mu FT, Moroi M, Gardiner EE, Berndt MC, Andrews RK. Al-Tamimi M, et al. Among authors: moroi m. Platelets. 2009 May;20(3):143-9. doi: 10.1080/09537100802710286. Platelets. 2009. PMID: 19437330 Free article.

4

Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets.

Poulter NS, Pollitt AY, Owen DM, Gardiner EE, Andrews RK, Shimizu H, Ishikawa D, Bihan D, Farndale RW, Moroi M, Watson SP, Jung SM. Poulter NS, et al. Among authors: moroi m. J Thromb Haemost. 2017 Mar;15(3):549-564. doi: 10.1111/jth.13613. Epub 2017 Feb 16. J Thromb Haemost. 2017. PMID: 28058806 Free PMC article.

5

Compromised ITAM-based platelet receptor function in a patient with immune thrombocytopenic purpura.

Gardiner EE, Al-Tamimi M, Mu FT, Karunakaran D, Thom JY, Moroi M, Andrews RK, Berndt MC, Baker RI. Gardiner EE, et al. Among authors: moroi m. J Thromb Haemost. 2008 Jul;6(7):1175-82. doi: 10.1111/j.1538-7836.2008.03016.x. Epub 2008 Jul 1. J Thromb Haemost. 2008. PMID: 18485087 Free article.

6

Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood.

Jung SM, Moroi M, Soejima K, Nakagaki T, Miura Y, Berndt MC, Gardiner EE, Howes JM, Pugh N, Bihan D, Watson SP, Farndale RW. Jung SM, et al. Among authors: moroi m. J Biol Chem. 2012 Aug 24;287(35):30000-13. doi: 10.1074/jbc.M112.359125. Epub 2012 Jul 6. J Biol Chem. 2012. PMID: 22773837 Free PMC article. Clinical Trial.

7

Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling.

Suzuki-Inoue K, Tulasne D, Shen Y, Bori-Sanz T, Inoue O, Jung SM, Moroi M, Andrews RK, Berndt MC, Watson SP. Suzuki-Inoue K, et al. Among authors: moroi m. J Biol Chem. 2002 Jun 14;277(24):21561-6. doi: 10.1074/jbc.M201012200. Epub 2002 Apr 9. J Biol Chem. 2002. PMID: 11943772 Free article.

8

Presence of platelet-associated anti-glycoprotein (GP)VI autoantibodies and restoration of GPVI expression in patients with GPVI deficiency.

Akiyama M, Kashiwagi H, Todo K, Moroi M, Berndt MC, Kojima H, Kanakura Y, Tomiyama Y. Akiyama M, et al. Among authors: moroi m. J Thromb Haemost. 2009 Aug;7(8):1373-83. doi: 10.1111/j.1538-7836.2009.03510.x. Epub 2009 Jun 9. J Thromb Haemost. 2009. PMID: 19522742 Free article.

9

Platelet receptors for collagen.

Moroi M, Jung SM. Moroi M, et al. Thromb Haemost. 1997 Jul;78(1):439-44. Thromb Haemost. 1997. PMID: 9198193 Review.

10

Dimers of the platelet collagen receptor glycoprotein VI bind specifically to fibrin fibers during clot formation, but not to intact fibrinogen.

Moroi M, Induruwa I, Farndale RW, Jung SM. Moroi M, et al. J Thromb Haemost. 2021 Aug;19(8):2056-2067. doi: 10.1111/jth.15399. Epub 2021 Jul 4. J Thromb Haemost. 2021. PMID: 34032355 Free article.

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