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Page 1
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.
Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvári B, Landt O, Schulz HU, Gress TM, Pfützer R, Löhr M, Kovacs P, Blüher M, Stumvoll M, Choudhuri G, Hegyi P, te Morsche RH, Drenth JP, Truninger K, Macek M Jr, Puhl G, Witt U, Schmidt H, Büning C, Ockenga J, Kage A, Groneberg DA, Nickel R, Berg T, Wiedenmann B, Bödeker H, Keim V, Mössner J, Teich N, Sahin-Tóth M. Rosendahl J, et al. Among authors: schulz hu. Nat Genet. 2008 Jan;40(1):78-82. doi: 10.1038/ng.2007.44. Epub 2007 Dec 2. Nat Genet. 2008. PMID: 18059268 Free PMC article.
HFE genotypes in patients with chronic pancreatitis and pancreatic adenocarcinoma.
Hucl T, Kylanpää-Bäck ML, Witt H, Künzli B, Lempinen M, Schneider A, Kemppainen E, Löhr M, Friess H, Ockenga J, Rosendahl J, Schulz HU, Gress T, Singer MV, Pfützer RH. Hucl T, et al. Among authors: schulz hu. Genet Med. 2007 Jul;9(7):479-83. doi: 10.1097/gim.0b013e3180986df4. Genet Med. 2007. PMID: 17666895 Free article. Clinical Trial.
Mutational analysis of the gene encoding the zymogen granule membrane glycoprotein 2 (GP2) in patients with chronic pancreatitis.
Witt H, Rosendahl J, te Morsche RH, Santhosh S, Chacko A, Schulz HU, Landt O, Teich N, Keim V, Mössner J, Gress TM, Ockenga J, Schmidt H, Kovacs P, Blüher M, Stumvoll M, Kage A, Groneberg DA, Jansen JB, Nickel R, Drenth JP. Witt H, et al. Among authors: schulz hu. Pancreas. 2010 Mar;39(2):188-92. doi: 10.1097/MPA.0b013e3181bd94ae. Pancreas. 2010. PMID: 19959969
Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.
Rosendahl J, Teich N, Kovacs P, Szmola R, Blüher M, Gress TM, Hoffmeister A, Keim V, Löhr M, Mössner J, Nickel R, Ockenga J, Pfützer R, Schulz HU, Stumvoll M, Wittenburg H, Sahin-Tóth M, Witt H. Rosendahl J, et al. Among authors: schulz hu. Pancreatology. 2010;10(2-3):243-9. doi: 10.1159/000243769. Epub 2010 May 13. Pancreatology. 2010. PMID: 20484962 Free PMC article.
A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis.
Rosendahl J, Tönjes A, Schleinitz D, Kovacs P, Wiegand J, Ruffert C, Jesinghaus M, Schober R, Herms M, Grützmann R, Schulz HU, Stickel F, Werner J, Bugert P, Blüher M, Stumvoll M, Böhm S, Berg T, Wittenburg H, Mössner J, te Morsche R, Derikx M, Keim V, Witt H, Drenth JP. Rosendahl J, et al. Among authors: schulz hu. PLoS One. 2012;7(1):e29433. doi: 10.1371/journal.pone.0029433. Epub 2012 Jan 20. PLoS One. 2012. PMID: 22276112 Free PMC article.
Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
Witt H, Beer S, Rosendahl J, Chen JM, Chandak GR, Masamune A, Bence M, Szmola R, Oracz G, Macek M Jr, Bhatia E, Steigenberger S, Lasher D, Bühler F, Delaporte C, Tebbing J, Ludwig M, Pilsak C, Saum K, Bugert P, Masson E, Paliwal S, Bhaskar S, Sobczynska-Tomaszewska A, Bak D, Balascak I, Choudhuri G, Nageshwar Reddy D, Rao GV, Thomas V, Kume K, Nakano E, Kakuta Y, Shimosegawa T, Durko L, Szabó A, Schnúr A, Hegyi P, Rakonczay Z Jr, Pfützer R, Schneider A, Groneberg DA, Braun M, Schmidt H, Witt U, Friess H, Algül H, Landt O, Schuelke M, Krüger R, Wiedenmann B, Schmidt F, Zimmer KP, Kovacs P, Stumvoll M, Blüher M, Müller T, Janecke A, Teich N, Grützmann R, Schulz HU, Mössner J, Keim V, Löhr M, Férec C, Sahin-Tóth M. Witt H, et al. Among authors: schulz hu. Nat Genet. 2013 Oct;45(10):1216-20. doi: 10.1038/ng.2730. Epub 2013 Aug 18. Nat Genet. 2013. PMID: 23955596 Free PMC article.
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis.
Witt H, Sahin-Tóth M, Landt O, Chen JM, Kähne T, Drenth JP, Kukor Z, Szepessy E, Halangk W, Dahm S, Rohde K, Schulz HU, Le Maréchal C, Akar N, Ammann RW, Truninger K, Bargetzi M, Bhatia E, Castellani C, Cavestro GM, Cerny M, Destro-Bisol G, Spedini G, Eiberg H, Jansen JB, Koudova M, Rausova E, Macek M Jr, Malats N, Real FX, Menzel HJ, Moral P, Galavotti R, Pignatti PF, Rickards O, Spicak J, Zarnescu NO, Böck W, Gress TM, Friess H, Ockenga J, Schmidt H, Pfützer R, Löhr M, Simon P, Weiss FU, Lerch MM, Teich N, Keim V, Berg T, Wiedenmann B, Luck W, Groneberg DA, Becker M, Keil T, Kage A, Bernardova J, Braun M, Güldner C, Halangk J, Rosendahl J, Witt U, Treiber M, Nickel R, Férec C. Witt H, et al. Among authors: schulz hu. Nat Genet. 2006 Jun;38(6):668-73. doi: 10.1038/ng1797. Epub 2006 May 14. Nat Genet. 2006. PMID: 16699518 Free PMC article.
Keratin 8 sequence variants in patients with pancreatitis and pancreatic cancer.
Treiber M, Schulz HU, Landt O, Drenth JP, Castellani C, Real FX, Akar N, Ammann RW, Bargetzi M, Bhatia E, Demaine AG, Battagia C, Kingsnorth A, O'Reilly D, Truninger K, Koudova M, Spicak J, Cerny M, Menzel HJ, Moral P, Pignatti PF, Romanelli MG, Rickards O, De Stefano GF, Zarnescu NO, Choudhuri G, Sikora SS, Jansen JB, Weiss FU, Pietschmann M, Teich N, Gress TM, Ockenga J, Schmidt H, Kage A, Halangk J, Rosendahl J, Groneberg DA, Nickel R, Witt H. Treiber M, et al. Among authors: schulz hu. J Mol Med (Berl). 2006 Dec;84(12):1015-22. doi: 10.1007/s00109-006-0096-7. Epub 2006 Oct 13. J Mol Med (Berl). 2006. PMID: 17039343 Free article.
The role of epoxide hydrolase Y113H gene variant in pancreatic diseases.
Ockenga J, Strunck S, Post C, Schulz HU, Halangk J, Pfützer RH, Löhr M, Oettle H, Kage A, Rosendahl J, Keim V, Drenth JP, Jansen JB, Lochs H, Witt H. Ockenga J, et al. Among authors: schulz hu. Pancreas. 2009 May;38(4):e97-e101. doi: 10.1097/MPA.0b013e31819feeed. Pancreas. 2009. PMID: 19287329
Angiotensin-converting enzyme insertion/deletion polymorphism in patients with acute and chronic pancreatitis.
Hucl T, Kylanpää ML, Künzli B, Witt H, Lempinen M, Schneider A, Kemppainen E, Löhr M, Haas SL, Friess H, Ockenga J, Rosendahl J, Schulz HU, Gress T, Singer MV, Pfützer RH. Hucl T, et al. Among authors: schulz hu. Eur J Gastroenterol Hepatol. 2009 Sep;21(9):1032-5. doi: 10.1097/MEG.0b013e328326f586. Eur J Gastroenterol Hepatol. 2009. PMID: 19307975
186 results