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4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG.
Strauss G, Westhoff MA, Fischer-Posovszky P, Fulda S, Schanbacher M, Eckhoff SM, Stahnke K, Vahsen N, Kroemer G, Debatin KM. Strauss G, et al. Among authors: westhoff ma. Cell Death Differ. 2008 Feb;15(2):332-43. doi: 10.1038/sj.cdd.4402272. Epub 2007 Nov 23. Cell Death Differ. 2008. PMID: 18034189
KIT mutations in primary mediastinal B-cell lymphoma.
Nagel PD, Stenzinger A, Feld FM, Herrmann MD, Brüderlein S, Barth TF, Marienfeld R, Endris V, Weichert W, Debatin KM, Westhoff MA, Lessel D, Möller P, Lennerz JK. Nagel PD, et al. Among authors: westhoff ma. Blood Cancer J. 2014 Aug 22;4(8):e241. doi: 10.1038/bcj.2014.61. Blood Cancer J. 2014. PMID: 25148223 Free PMC article. No abstract available.
Tonabersat enhances temozolomide-mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition.
Schmidt ENC, Evert BO, Pregler BEF, Melhem A, Hsieh MC, Raspe M, Strobel H, Roos J, Pietsch T, Schuss P, Fischer-Posovszky P, Westhoff MA, Hölzel M, Herrlinger U, Vatter H, Waha A, Schneider M, Potthoff AL. Schmidt ENC, et al. Among authors: westhoff ma. Mol Oncol. 2024 Dec 16. doi: 10.1002/1878-0261.13786. Online ahead of print. Mol Oncol. 2024. PMID: 39680504 Free article.
Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma.
Freitag T, Kaps P, Ramtke J, Bertels S, Zunke E, Schneider B, Becker AS, Koczan D, Dubinski D, Freiman TM, Wittig F, Hinz B, Westhoff MA, Strobel H, Meiners F, Wolter D, Engel N, Troschke-Meurer S, Bergmann-Ewert W, Staehlke S, Wolff A, Gessler F, Junghanss C, Maletzki C. Freitag T, et al. Among authors: westhoff ma. NPJ Precis Oncol. 2024 Jul 25;8(1):156. doi: 10.1038/s41698-024-00653-3. NPJ Precis Oncol. 2024. PMID: 39054369 Free PMC article.
104 results