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Page 1
Unraveling Hematotoxicity of α-Amanitin in Cultured Hematopoietic Cells.
Hof WFJ, Visser M, de Jong JJ, Rajasekar MN, Schuringa JJ, de Graaf IAM, Touw DJ, Dekkers BGJ. Hof WFJ, et al. Among authors: de graaf iam. Toxins (Basel). 2024 Jan 22;16(1):61. doi: 10.3390/toxins16010061. Toxins (Basel). 2024. PMID: 38276537 Free PMC article.
Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits.
Estrada-Ortiz N, Starokozhko V, van Steenwijk H, van der Heide C, Permentier H, van Heemskerk L, Prins GH, Heegsma J, Faber KN, Bressers S, Steiblen G, de Groot A, Groome S, van Miert E, Groothuis G, de Graaf IAM. Estrada-Ortiz N, et al. Among authors: de graaf iam. J Appl Toxicol. 2022 Dec;42(12):1921-1936. doi: 10.1002/jat.4364. Epub 2022 Aug 24. J Appl Toxicol. 2022. PMID: 35857281 Free PMC article.
Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation.
Lkhagvadorj K, Zeng Z, Meyer KF, Verweij LP, Kooistra W, Reinders-Luinge M, Dijkhuizen HW, de Graaf IAM, Plösch T, Hylkema MN. Lkhagvadorj K, et al. Among authors: de graaf iam. Int J Mol Sci. 2020 Dec 26;22(1):164. doi: 10.3390/ijms22010164. Int J Mol Sci. 2020. PMID: 33375250 Free PMC article.
Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring.
Lkhagvadorj K, Meyer KF, Verweij LP, Kooistra W, Reinders-Luinge M, Dijkhuizen HW, de Graaf IAM, Plösch T, Hylkema MN. Lkhagvadorj K, et al. Among authors: de graaf iam. Epigenetics. 2020 Dec;15(12):1370-1385. doi: 10.1080/15592294.2020.1782655. Epub 2020 Jun 23. Epigenetics. 2020. PMID: 32573327 Free PMC article.
Glutathione-responsive cyclodextrin-nanosponges as drug delivery systems for doxorubicin: Evaluation of toxicity and transport mechanisms in the liver.
Daga M, de Graaf IAM, Argenziano M, Barranco ASM, Loeck M, Al-Adwi Y, Cucci MA, Caldera F, Trotta F, Barrera G, Casini A, Cavalli R, Pizzimenti S. Daga M, et al. Among authors: de graaf iam. Toxicol In Vitro. 2020 Jun;65:104800. doi: 10.1016/j.tiv.2020.104800. Epub 2020 Feb 19. Toxicol In Vitro. 2020. PMID: 32084521 Free article.
Development of a Novel Ex-vivo 3D Model to Screen Amoebicidal Activity on Infected Tissue.
Guzmán-Delgado NE, Carranza-Torres IE, García-Davis S, Rivera G, Morán-Martínez J, Betancourt-Martínez ND, Groothuis GMM, de Graaf IAM, Carranza-Rosales P. Guzmán-Delgado NE, et al. Among authors: de graaf iam. Sci Rep. 2019 Jun 10;9(1):8396. doi: 10.1038/s41598-019-44899-5. Sci Rep. 2019. PMID: 31182753 Free PMC article.
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