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Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.
Pinheiro SV, Simões e Silva AC, Sampaio WO, de Paula RD, Mendes EP, Bontempo ED, Pesquero JB, Walther T, Alenina N, Bader M, Bleich M, Santos RA. Pinheiro SV, et al. Among authors: santos ra. Hypertension. 2004 Oct;44(4):490-6. doi: 10.1161/01.HYP.0000141438.64887.42. Epub 2004 Aug 23. Hypertension. 2004. PMID: 15326087
Vascular relaxation, antihypertensive effect, and cardioprotection of a novel peptide agonist of the MAS receptor.
Savergnini SQ, Beiman M, Lautner RQ, de Paula-Carvalho V, Allahdadi K, Pessoa DC, Costa-Fraga FP, Fraga-Silva RA, Cojocaru G, Cohen Y, Bader M, de Almeida AP, Rotman G, Santos RA. Savergnini SQ, et al. Among authors: santos ra. Hypertension. 2010 Jul;56(1):112-20. doi: 10.1161/HYPERTENSIONAHA.110.152942. Epub 2010 May 17. Hypertension. 2010. PMID: 20479330
The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension.
Shenoy V, Ferreira AJ, Qi Y, Fraga-Silva RA, Díez-Freire C, Dooies A, Jun JY, Sriramula S, Mariappan N, Pourang D, Venugopal CS, Francis J, Reudelhuber T, Santos RA, Patel JM, Raizada MK, Katovich MJ. Shenoy V, et al. Among authors: santos ra. Am J Respir Crit Care Med. 2010 Oct 15;182(8):1065-72. doi: 10.1164/rccm.200912-1840OC. Epub 2010 Jun 25. Am J Respir Crit Care Med. 2010. PMID: 20581171 Free PMC article.
Altered regional blood flow distribution in Mas-deficient mice.
Botelho-Santos GA, Bader M, Alenina N, Santos RA. Botelho-Santos GA, et al. Among authors: santos ra. Ther Adv Cardiovasc Dis. 2012 Oct;6(5):201-11. doi: 10.1177/1753944712461164. Ther Adv Cardiovasc Dis. 2012. PMID: 23045193 Free article.
751 results