Díaz-Gavilán M - Search Results

1

Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin-3-ylmethyl)-9H-purines.

Díaz-Gavilán M, Conejo-García A, Cruz-López O, Núñez MC, Choquesillo-Lazarte D, González-Pérez JM, Rodríguez-Serrano F, Marchal JA, Aránega A, Gallo MA, Espinosa A, Campos JM. Díaz-Gavilán M, et al. ChemMedChem. 2008 Jan;3(1):127-35. doi: 10.1002/cmdc.200700180. ChemMedChem. 2008. PMID: 18022976

2

Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies.

Díaz-Gavilán M, Gómez-Vidal JA, Rodríguez-Serrano F, Marchal JA, Caba O, Aránega A, Gallo MA, Espinosa A, Campos JM. Díaz-Gavilán M, et al. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1457-60. doi: 10.1016/j.bmcl.2007.12.070. Epub 2008 Jan 1. Bioorg Med Chem Lett. 2008. PMID: 18194866

3

Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines.

Núñez MC, Díaz-Gavilán M, Conejo-García A, Cruz-López O, Gallo MA, Espinosa A, Campos JM. Núñez MC, et al. Curr Med Chem. 2008;15(25):2614-31. doi: 10.2174/092986708785909021. Curr Med Chem. 2008. PMID: 18855682 Review.

4

Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine.

Caba O, Díaz-Gavilán M, Rodríguez-Serrano F, Boulaiz H, Aránega A, Gallo MA, Marchal JA, Campos JM. Caba O, et al. Eur J Med Chem. 2011 Sep;46(9):3802-9. doi: 10.1016/j.ejmech.2011.05.047. Epub 2011 May 27. Eur J Med Chem. 2011. PMID: 21684047

5

A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells.

Marchal JA, Núñez MC, Suárez I, Díaz-Gavilán M, Gómez-Vidal JA, Boulaiz H, Rodríguez-Serrano F, Gallo MA, Espinosa A, Aránega A, Campos JM. Marchal JA, et al. Breast Cancer Res Treat. 2007 Nov;105(3):237-46. doi: 10.1007/s10549-006-9450-2. Epub 2006 Nov 24. Breast Cancer Res Treat. 2007. PMID: 17124554

6

The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis.

Caba O, Rodríguez-Serrano F, Díaz-Gavilán M, Conejo-García A, Ortiz R, Martínez-Amat A, Alvarez P, Gallo MA, Campos JM, Marchal JA, Aránega A. Caba O, et al. Among authors: diaz gavilan m. Eur J Med Chem. 2012 Apr;50:376-82. doi: 10.1016/j.ejmech.2012.02.017. Epub 2012 Feb 17. Eur J Med Chem. 2012. PMID: 22373735

7

From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: the shift from differentiating anticancer agents to apoptotic inducers.

Conejo-García A, Núñez Mdel C, Díaz-Gavilán M, Cruz-López O, Gallo MÁ, Espinosa A, Campos JM. Conejo-García A, et al. Expert Opin Drug Discov. 2008 Oct;3(10):1223-35. doi: 10.1517/17460441.3.10.1223. Expert Opin Drug Discov. 2008. PMID: 23489079

8

Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom.

Díaz-Gavilán M, Gómez-Vidal JA, Entrena A, Gallo MA, Espinosa A, Campos JM. Díaz-Gavilán M, et al. J Org Chem. 2006 Feb 3;71(3):1043-54. doi: 10.1021/jo052167m. J Org Chem. 2006. PMID: 16438519

9

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1.

Moya-Garzón MD, Martín Higueras C, Peñalver P, Romera M, Fernandes MX, Franco-Montalbán F, Gómez-Vidal JA, Salido E, Díaz-Gavilán M. Moya-Garzón MD, et al. Among authors: diaz gavilan m. J Med Chem. 2018 Aug 23;61(16):7144-7167. doi: 10.1021/acs.jmedchem.8b00399. Epub 2018 Aug 6. J Med Chem. 2018. PMID: 30028141

10

O-Alkyl Hydroxamates Display Potent and Selective Antileishmanial Activity.

Corpas-López V, Tabraue-Chávez M, Sixto-López Y, Panadero-Fajardo S, Alves de Lima Franco F, Domínguez-Seglar JF, Morillas-Márquez F, Franco-Montalbán F, Díaz-Gavilán M, Correa-Basurto J, López-Viota J, López-Viota M, Pérez Del Palacio J, de la Cruz M, de Pedro N, Martín-Sánchez J, Gómez-Vidal JA. Corpas-López V, et al. Among authors: diaz gavilan m. J Med Chem. 2020 Jun 11;63(11):5734-5751. doi: 10.1021/acs.jmedchem.9b02016. Epub 2020 May 26. J Med Chem. 2020. PMID: 32392053

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