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Inhibition of the chemokine receptors CXCR1 and CXCR2 synergizes with docetaxel for effective tumor control and remodeling of the immune microenvironment of HPV-negative head and neck cancer models.
Horn LA, Lind H, Fousek K, Qin H, Rajabian N, Angstadt S, Hsiao-Sanchez N, Medina-Enriquez MM, Kelly MD, Allen CT, Hammoudeh SM, Weigert R, Maeda DY, Zebala JA, Palena C. Horn LA, et al. Among authors: zebala ja. J Exp Clin Cancer Res. 2024 Dec 5;43(1):318. doi: 10.1186/s13046-024-03240-3. J Exp Clin Cancer Res. 2024. PMID: 39639338 Free PMC article.
Tumor-induced endothelial RhoA activation mediates tumor cell transendothelial migration and metastasis.
Sajib MS, Zahra FT, Lamprou M, Akwii RG, Park JH, Osorio M, Tullar P, Doci CL, Zhang C, Huveneers S, Van Buul JD, Wang MH, Markiewski MM, Srivastava SK, Zheng Y, Gutkind JS, Hu J, Bickel U, Maeda DY, Zebala JA, Lionakis MS, Trasti S, Mikelis CM. Sajib MS, et al. Among authors: zebala ja. bioRxiv [Preprint]. 2024 Sep 24:2024.09.22.614304. doi: 10.1101/2024.09.22.614304. bioRxiv. 2024. PMID: 39372784 Free PMC article. Preprint.
CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth.
Yang J, Bergdorf K, Yan C, Luo W, Chen SC, Ayers D, Liu Q, Liu X, Boothby M, Groves SM, Oleskie AN, Zhang X, Maeda DY, Zebala JA, Quaranta V, Richmond A. Yang J, et al. Among authors: zebala ja. bioRxiv [Preprint]. 2023 Mar 4:2023.02.22.529548. doi: 10.1101/2023.02.22.529548. bioRxiv. 2023. Update in: Mol Cancer. 2023 Jun 3;22(1):92. doi: 10.1186/s12943-023-01789-9. PMID: 36865260 Free PMC article. Updated. Preprint.
Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer.
Gulhati P, Schalck A, Jiang S, Shang X, Wu CJ, Hou P, Ruiz SH, Soto LS, Parra E, Ying H, Han J, Dey P, Li J, Deng P, Sei E, Maeda DY, Zebala JA, Spring DJ, Kim M, Wang H, Maitra A, Moore D, Clise-Dwyer K, Wang YA, Navin NE, DePinho RA. Gulhati P, et al. Among authors: zebala ja. Nat Cancer. 2023 Jan;4(1):62-80. doi: 10.1038/s43018-022-00500-z. Epub 2022 Dec 30. Nat Cancer. 2023. PMID: 36585453 Free PMC article.
36 results