Shokat KM - Search Results

1

A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration.

Snead JL, Sullivan M, Lowery DM, Cohen MS, Zhang C, Randle DH, Taunton J, Yaffe MB, Morgan DO, Shokat KM. Snead JL, et al. Among authors: shokat km. Chem Biol. 2007 Nov;14(11):1261-72. doi: 10.1016/j.chembiol.2007.09.011. Chem Biol. 2007. PMID: 18022565 Free PMC article.

2

Structural basis for selective inhibition of Src family kinases by PP1.

Liu Y, Bishop A, Witucki L, Kraybill B, Shimizu E, Tsien J, Ubersax J, Blethrow J, Morgan DO, Shokat KM. Liu Y, et al. Among authors: shokat km. Chem Biol. 1999 Sep;6(9):671-8. doi: 10.1016/s1074-5521(99)80118-5. Chem Biol. 1999. PMID: 10467133 Free article.

3

A chemical switch for inhibitor-sensitive alleles of any protein kinase.

Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM. Bishop AC, et al. Among authors: shokat km. Nature. 2000 Sep 21;407(6802):395-401. doi: 10.1038/35030148. Nature. 2000. PMID: 11014197

4

Chemical genetic analysis of the budding-yeast p21-activated kinase Cla4p.

Weiss EL, Bishop AC, Shokat KM, Drubin DG. Weiss EL, et al. Among authors: shokat km. Nat Cell Biol. 2000 Oct;2(10):677-85. doi: 10.1038/35036300. Nat Cell Biol. 2000. PMID: 11025657

5

Chemical genetic approaches for the elucidation of signaling pathways.

Alaimo PJ, Shogren-Knaak MA, Shokat KM. Alaimo PJ, et al. Among authors: shokat km. Curr Opin Chem Biol. 2001 Aug;5(4):360-7. doi: 10.1016/s1367-5931(00)00215-5. Curr Opin Chem Biol. 2001. PMID: 11470597 Review.

6

Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response.

Carroll AS, Bishop AC, DeRisi JL, Shokat KM, O'Shea EK. Carroll AS, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12578-83. doi: 10.1073/pnas.211195798. Proc Natl Acad Sci U S A. 2001. PMID: 11675494 Free PMC article.

7

Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme.

Witucki LA, Huang X, Shah K, Liu Y, Kyin S, Eck MJ, Shokat KM. Witucki LA, et al. Among authors: shokat km. Chem Biol. 2002 Jan;9(1):25-33. doi: 10.1016/s1074-5521(02)00091-1. Chem Biol. 2002. PMID: 11841936

8

A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway.

Shah K, Shokat KM. Shah K, et al. Among authors: shokat km. Chem Biol. 2002 Jan;9(1):35-47. doi: 10.1016/s1074-5521(02)00086-8. Chem Biol. 2002. PMID: 11841937 Free article.

9

The emerging power of chemical genetics.

Specht KM, Shokat KM. Specht KM, et al. Among authors: shokat km. Curr Opin Cell Biol. 2002 Apr;14(2):155-9. doi: 10.1016/s0955-0674(02)00317-4. Curr Opin Cell Biol. 2002. PMID: 11891113 Review.

10

Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity.

Niswender CM, Ishihara RW, Judge LM, Zhang C, Shokat KM, McKnight GS. Niswender CM, et al. Among authors: shokat km. J Biol Chem. 2002 Aug 9;277(32):28916-22. doi: 10.1074/jbc.M203327200. Epub 2002 May 28. J Biol Chem. 2002. PMID: 12034735 Free article.

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