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Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.
Lauring J, Cosgrove DP, Fontana S, Gustin JP, Konishi H, Abukhdeir AM, Garay JP, Mohseni M, Wang GM, Higgins MJ, Gorkin D, Reis M, Vogelstein B, Polyak K, Cowherd M, Buckhaults PJ, Park BH. Lauring J, et al. Among authors: konishi h. Oncogene. 2010 Apr 22;29(16):2337-45. doi: 10.1038/onc.2009.516. Epub 2010 Jan 25. Oncogene. 2010. PMID: 20101210 Free PMC article.
Tamoxifen-stimulated growth of breast cancer due to p21 loss.
Abukhdeir AM, Vitolo MI, Argani P, De Marzo AM, Karakas B, Konishi H, Gustin JP, Lauring J, Garay JP, Pendleton C, Konishi Y, Blair BG, Brenner K, Garrett-Mayer E, Carraway H, Bachman KE, Park BH. Abukhdeir AM, et al. Among authors: konishi h, konishi y. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):288-93. doi: 10.1073/pnas.0710887105. Epub 2007 Dec 27. Proc Natl Acad Sci U S A. 2008. PMID: 18162533 Free PMC article.
Knockin of mutant PIK3CA activates multiple oncogenic pathways.
Gustin JP, Karakas B, Weiss MB, Abukhdeir AM, Lauring J, Garay JP, Cosgrove D, Tamaki A, Konishi H, Konishi Y, Mohseni M, Wang G, Rosen DM, Denmeade SR, Higgins MJ, Vitolo MI, Bachman KE, Park BH. Gustin JP, et al. Among authors: konishi h, konishi y. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2835-40. doi: 10.1073/pnas.0813351106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196980 Free PMC article.
PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells.
Higgins MJ, Beaver JA, Wong HY, Gustin JP, Lauring JD, Garay JP, Konishi H, Mohseni M, Wang GM, Cidado J, Jelovac D, Cosgrove DP, Tamaki A, Abukhdeir AM, Park BH. Higgins MJ, et al. Among authors: konishi h. Cancer Biol Ther. 2011 Feb 1;11(3):358-67. doi: 10.4161/cbt.11.3.14227. Epub 2011 Feb 1. Cancer Biol Ther. 2011. PMID: 21124076 Free PMC article.
1,612 results