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Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis.
Segrelles C, Lu J, Hammann B, Santos M, Moral M, Cascallana JL, Lara MF, Rho O, Carbajal S, Traag J, Beltrán L, Martínez-Cruz AB, García-Escudero R, Lorz C, Ruiz S, Bravo A, Paramio JM, DiGiovanni J. Segrelles C, et al. Among authors: digiovanni j. Cancer Res. 2007 Nov 15;67(22):10879-88. doi: 10.1158/0008-5472.CAN-07-2564. Cancer Res. 2007. PMID: 18006833
Role of the epidermal growth factor receptor and transforming growth factor alpha in mouse skin carcinogenesis.
DiGiovanni J, Rho O, Xian W, Beltràn L. DiGiovanni J, et al. Prog Clin Biol Res. 1994;387:113-38. Prog Clin Biol Res. 1994. PMID: 7972243 Review.
The rasHa gene, and to a limited extent the N-ras gene, have been identified as target genes for certain tumor initiators in this model system (reviewed in DiGiovanni 1992). The promotion stage of mouse skin carcinogenesis involves the production and maintenance of a chron …
The rasHa gene, and to a limited extent the N-ras gene, have been identified as target genes for certain tumor initiators in this model syst …
358 results