Yagen B - Search Results

1

Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.

Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Shimshoni JA, et al. Among authors: yagen b. J Med Chem. 2007 Dec 13;50(25):6419-27. doi: 10.1021/jm7009233. Epub 2007 Nov 10. J Med Chem. 2007. PMID: 17994680

2

Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.

Isoherranen N, Yagen B, Woodhead JH, Spiegelstein O, Blotnik S, Wilcox KS, Finnell RH, Bennett GD, White HS, Bialer M. Isoherranen N, et al. Among authors: yagen b. Br J Pharmacol. 2003 Feb;138(4):602-13. doi: 10.1038/sj.bjp.0705076. Br J Pharmacol. 2003. PMID: 12598414 Free PMC article.

3

New CNS-active drugs which are second-generation valproic acid: can they lead to the development of a magic bullet?

Isoherranen N, Yagen B, Bialer M. Isoherranen N, et al. Among authors: yagen b. Curr Opin Neurol. 2003 Apr;16(2):203-11. doi: 10.1097/01.wco.0000063774.81810.30. Curr Opin Neurol. 2003. PMID: 12644750 Review.

4

Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.

Isoherranen N, Yagen B, Spiegelstein O, Finnell RH, Merriweather M, Woodhead JH, Wlodarczyk B, White HS, Bialer M. Isoherranen N, et al. Among authors: yagen b. Br J Pharmacol. 2003 Jun;139(4):755-64. doi: 10.1038/sj.bjp.0705301. Br J Pharmacol. 2003. PMID: 12812999 Free PMC article.

5

Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.

Sobol E, Bialer M, Yagen B. Sobol E, et al. Among authors: yagen b. J Med Chem. 2004 Aug 12;47(17):4316-26. doi: 10.1021/jm0498351. J Med Chem. 2004. PMID: 15294003

6

Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives.

Eyal S, Yagen B, Shimshoni J, Bialer M. Eyal S, et al. Among authors: yagen b. Biochem Pharmacol. 2005 May 15;69(10):1501-8. doi: 10.1016/j.bcp.2005.02.012. Biochem Pharmacol. 2005. PMID: 15857614

7

Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain.

Winkler I, Blotnik S, Shimshoni J, Yagen B, Devor M, Bialer M. Winkler I, et al. Among authors: yagen b. Br J Pharmacol. 2005 Sep;146(2):198-208. doi: 10.1038/sj.bjp.0706310. Br J Pharmacol. 2005. PMID: 15997234 Free PMC article.

8

Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain.

Winkler I, Sobol E, Yagen B, Steinman A, Devor M, Bialer M. Winkler I, et al. Among authors: yagen b. Neuropharmacology. 2005 Dec;49(8):1110-20. doi: 10.1016/j.neuropharm.2005.06.008. Epub 2005 Aug 1. Neuropharmacology. 2005. PMID: 16055160

9

Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.

Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M. Sobol E, et al. Among authors: yagen b. Neuropharmacology. 2006 Sep;51(4):933-46. doi: 10.1016/j.neuropharm.2006.06.006. Epub 2006 Aug 4. Neuropharmacology. 2006. PMID: 16890251

10

Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.

Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M. Sobol E, et al. Among authors: yagen b. Epilepsy Res. 2007 Jan;73(1):75-84. doi: 10.1016/j.eplepsyres.2006.08.004. Epub 2006 Sep 25. Epilepsy Res. 2007. PMID: 16997532

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