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Inhibition of transforming growth factor-beta signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart.
Lucas JA, Zhang Y, Li P, Gong K, Miller AP, Hassan E, Hage F, Xing D, Wells B, Oparil S, Chen YF. Lucas JA, et al. Among authors: li p. Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H424-32. doi: 10.1152/ajpheart.00529.2009. Epub 2009 Nov 20. Am J Physiol Heart Circ Physiol. 2010. PMID: 19933419 Free PMC article.
Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling.
Gong K, Xing D, Li P, Aksut B, Ambalavanan N, Yang Q, Nozell SE, Oparil S, Chen YF. Gong K, et al. Among authors: li p. Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L899-907. doi: 10.1152/ajplung.00062.2011. Epub 2011 Sep 16. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21926264 Free PMC article.
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