Metcalf WW - Search Results

1

Reassignment of the structure of the antibiotic A53868 reveals an unusual amino dehydrophosphonic acid.

Whitteck JT, Ni W, Griffin BM, Eliot AC, Thomas PM, Kelleher NL, Metcalf WW, van der Donk WA. Whitteck JT, et al. Among authors: metcalf ww. Angew Chem Int Ed Engl. 2007;46(47):9089-92. doi: 10.1002/anie.200703810. Angew Chem Int Ed Engl. 2007. PMID: 17990255 No abstract available.

2

Phosphite dehydrogenase: an unusual phosphoryl transfer reaction.

Vrtis JM, White AK, Metcalf WW, van der Donk WA. Vrtis JM, et al. Among authors: metcalf ww. J Am Chem Soc. 2001 Mar 21;123(11):2672-3. doi: 10.1021/ja004301k. J Am Chem Soc. 2001. PMID: 11456941 No abstract available.

3

Phosphite dehydrogenase: a versatile cofactor-regeneration enzyme.

Vrtis JM, White AK, Metcalf WW, van der Donk WA. Vrtis JM, et al. Among authors: metcalf ww. Angew Chem Int Ed Engl. 2002 Sep 2;41(17):3257-9. doi: 10.1002/1521-3773(20020902)41:17<3257::AID-ANIE3257>3.0.CO;2-N. Angew Chem Int Ed Engl. 2002. PMID: 12207407 No abstract available.

4

Top down mass spectrometry of < 60-kDa proteins from Methanosarcina acetivorans using quadrupole FRMS with automated octopole collisionally activated dissociation.

Patrie SM, Ferguson JT, Robinson DE, Whipple D, Rother M, Metcalf WW, Kelleher NL. Patrie SM, et al. Among authors: metcalf ww. Mol Cell Proteomics. 2006 Jan;5(1):14-25. doi: 10.1074/mcp.M500219-MCP200. Mol Cell Proteomics. 2006. PMID: 16236702 Free article.

5

Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster.

Woodyer RD, Shao Z, Thomas PM, Kelleher NL, Blodgett JA, Metcalf WW, van der Donk WA, Zhao H. Woodyer RD, et al. Among authors: metcalf ww. Chem Biol. 2006 Nov;13(11):1171-82. doi: 10.1016/j.chembiol.2006.09.007. Chem Biol. 2006. PMID: 17113999

6

Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.

Blodgett JA, Thomas PM, Li G, Velasquez JE, van der Donk WA, Kelleher NL, Metcalf WW. Blodgett JA, et al. Among authors: metcalf ww. Nat Chem Biol. 2007 Aug;3(8):480-5. doi: 10.1038/nchembio.2007.9. Epub 2007 Jul 15. Nat Chem Biol. 2007. PMID: 17632514 Free PMC article.

7

Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways.

Shao Z, Blodgett JA, Circello BT, Eliot AC, Woodyer R, Li G, van der Donk WA, Metcalf WW, Zhao H. Shao Z, et al. Among authors: metcalf ww. J Biol Chem. 2008 Aug 22;283(34):23161-8. doi: 10.1074/jbc.M801788200. Epub 2008 Jun 10. J Biol Chem. 2008. PMID: 18544530 Free PMC article.

8

Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098.

Eliot AC, Griffin BM, Thomas PM, Johannes TW, Kelleher NL, Zhao H, Metcalf WW. Eliot AC, et al. Among authors: metcalf ww. Chem Biol. 2008 Aug 25;15(8):765-70. doi: 10.1016/j.chembiol.2008.07.010. Chem Biol. 2008. PMID: 18721747 Free PMC article.

9

Biosynthesis of phosphonic and phosphinic acid natural products.

Metcalf WW, van der Donk WA. Metcalf WW, et al. Annu Rev Biochem. 2009;78:65-94. doi: 10.1146/annurev.biochem.78.091707.100215. Annu Rev Biochem. 2009. PMID: 19489722 Free PMC article. Review.

10

An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis.

Cicchillo RM, Zhang H, Blodgett JA, Whitteck JT, Li G, Nair SK, van der Donk WA, Metcalf WW. Cicchillo RM, et al. Among authors: metcalf ww. Nature. 2009 Jun 11;459(7248):871-4. doi: 10.1038/nature07972. Nature. 2009. PMID: 19516340 Free PMC article.

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