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Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice.
Kamsler A, Daily D, Hochman A, Stern N, Shiloh Y, Rotman G, Barzilai A. Kamsler A, et al. Among authors: shiloh y. Cancer Res. 2001 Mar 1;61(5):1849-54. Cancer Res. 2001. PMID: 11280737
We previously hypothesized that some aspects of A-T, such as the preferential loss of certain neurons, could result from a continuous state of increased oxidative stress (G. Rotman and Y. Shiloh, Cancer Surv., 29: 285-304, 1997; G. Rotman and Y. Shiloh
We previously hypothesized that some aspects of A-T, such as the preferential loss of certain neurons, could result from a continuous state …
Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia.
Ziv S, Brenner O, Amariglio N, Smorodinsky NI, Galron R, Carrion DV, Zhang W, Sharma GG, Pandita RK, Agarwal M, Elkon R, Katzin N, Bar-Am I, Pandita TK, Kucherlapati R, Rechavi G, Shiloh Y, Barzilai A. Ziv S, et al. Among authors: shiloh y. Hum Mol Genet. 2005 Oct 1;14(19):2929-43. doi: 10.1093/hmg/ddi324. Epub 2005 Sep 8. Hum Mol Genet. 2005. PMID: 16150740
241 results