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Inverse agonist properties of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide HCl (SR141716A) and 1-(2-chlorophenyl)-4-cyano-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxyl ic acid phenylamide (CP-272871) for the CB(1) cannabinoid receptor.
Meschler JP, Kraichely DM, Wilken GH, Howlett AC. Meschler JP, et al. Among authors: wilken gh. Biochem Pharmacol. 2000 Nov 1;60(9):1315-23. doi: 10.1016/s0006-2952(00)00447-0. Biochem Pharmacol. 2000. PMID: 11008125
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