Dix MC - Search Results

1

Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38alpha(MAPK) inhibitors in Werner syndrome cells.

Davis T, Bagley MC, Dix MC, Murziani PG, Rokicki MJ, Widdowson CS, Zayed JM, Bachler MA, Kipling D. Davis T, et al. Among authors: dix mc. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6832-5. doi: 10.1016/j.bmcl.2007.10.036. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17964780

2

Microwave-assisted synthesis of N-pyrazole ureas and the p38alpha inhibitor BIRB 796 for study into accelerated cell ageing.

Bagley MC, Davis T, Dix MC, Widdowson CS, Kipling D. Bagley MC, et al. Among authors: dix mc. Org Biomol Chem. 2006 Nov 21;4(22):4158-64. doi: 10.1039/b611493h. Org Biomol Chem. 2006. PMID: 17312972

3

Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells.

Bagley MC, Davis T, Dix MC, Rokicki MJ, Kipling D. Bagley MC, et al. Among authors: dix mc. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5107-10. doi: 10.1016/j.bmcl.2007.07.016. Epub 2007 Jul 13. Bioorg Med Chem Lett. 2007. PMID: 17659871

4

Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38(MAPK) inhibitor RO3201195 for study in Werner syndrome cells.

Bagley MC, Davis T, Dix MC, Murziani PG, Rokicki MJ, Kipling D. Bagley MC, et al. Among authors: dix mc. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3745-8. doi: 10.1016/j.bmcl.2008.05.037. Epub 2008 May 16. Bioorg Med Chem Lett. 2008. PMID: 18539026

5

Microwave-assisted Ullmann C-S bond formation: synthesis of the P38alpha MAPK clinical candidate VX-745.

Bagley MC, Davis T, Dix MC, Fusillo V, Pigeaux M, Rokicki MJ, Kipling D. Bagley MC, et al. Among authors: dix mc. J Org Chem. 2009 Nov 6;74(21):8336-42. doi: 10.1021/jo9017155. J Org Chem. 2009. PMID: 19778055

6

Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome.

Bagley MC, Davis T, Dix MC, Fusillo V, Pigeaux M, Rokicki MJ, Kipling D. Bagley MC, et al. Among authors: dix mc. Future Med Chem. 2010 Sep;2(9):1417-27. doi: 10.4155/fmc.10.217. Future Med Chem. 2010. PMID: 21426137

7

Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells.

Bagley MC, Davis T, Dix MC, Murziani PG, Rokicki MJ, Kipling D. Bagley MC, et al. Among authors: dix mc. Future Med Chem. 2010 Feb;2(2):203-13. doi: 10.4155/fmc.09.160. Future Med Chem. 2010. PMID: 21426187

8

Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors.

Davis T, Dix MC, Rokicki MJ, Brook AJ, Widdowson CS, Kipling D, Bagley MC. Davis T, et al. Among authors: dix mc. Chem Cent J. 2011 Dec 8;5(1):83. doi: 10.1186/1752-153X-5-83. Chem Cent J. 2011. PMID: 22152108 Free PMC article.

9

The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells.

Bagley MC, Dwyer JE, Baashen M, Dix MC, Murziani PG, Rokicki MJ, Kipling D, Davis T. Bagley MC, et al. Among authors: dix mc. Org Biomol Chem. 2016 Jan 21;14(3):947-56. doi: 10.1039/c5ob02229k. Epub 2015 Nov 27. Org Biomol Chem. 2016. PMID: 26611938

10

Differential antibody responses in 6.B major histocompatibility (B) complex congenic chickens.

Dix MC, Taylor RL Jr. Dix MC, et al. Poult Sci. 1996 Feb;75(2):203-7. doi: 10.3382/ps.0750203. Poult Sci. 1996. PMID: 8833372 Free article.

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