James MF - Search Results

1

Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth.

James MF, Lelke JM, Maccollin M, Plotkin SR, Stemmer-Rachamimov AO, Ramesh V, Gusella JF. James MF, et al. Neurobiol Dis. 2008 Feb;29(2):278-92. doi: 10.1016/j.nbd.2007.09.002. Epub 2007 Sep 19. Neurobiol Dis. 2008. PMID: 17962031 Free PMC article.

2

NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth.

James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V. James MF, et al. Mol Cell Biol. 2009 Aug;29(15):4250-61. doi: 10.1128/MCB.01581-08. Epub 2009 May 18. Mol Cell Biol. 2009. PMID: 19451225 Free PMC article.

3

Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types.

James MF, Stivison E, Beauchamp R, Han S, Li H, Wallace MR, Gusella JF, Stemmer-Rachamimov AO, Ramesh V. James MF, et al. Mol Cancer Res. 2012 May;10(5):649-59. doi: 10.1158/1541-7786.MCR-11-0425-T. Epub 2012 Mar 16. Mol Cancer Res. 2012. PMID: 22426462

4

Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2.

Wiederhold T, Lee MF, James M, Neujahr R, Smith N, Murthy A, Hartwig J, Gusella JF, Ramesh V. Wiederhold T, et al. Among authors: james m. Oncogene. 2004 Nov 18;23(54):8815-25. doi: 10.1038/sj.onc.1208110. Oncogene. 2004. PMID: 15467741

5

Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas.

Shen Y, Nunes F, Stemmer-Rachamimov A, James M, Mohapatra G, Plotkin S, Betensky RA, Engler DA, Roy J, Ramesh V, Gusella JF. Shen Y, et al. BMC Med Genomics. 2009 Jul 9;2:42. doi: 10.1186/1755-8794-2-42. BMC Med Genomics. 2009. PMID: 19589153 Free PMC article.

6

The NF2 tumor suppressor Merlin and the ERM proteins interact with N-WASP and regulate its actin polymerization function.

Manchanda N, Lyubimova A, Ho HY, James MF, Gusella JF, Ramesh N, Snapper SB, Ramesh V. Manchanda N, et al. Among authors: james mf. J Biol Chem. 2005 Apr 1;280(13):12517-22. doi: 10.1074/jbc.C400583200. Epub 2005 Feb 7. J Biol Chem. 2005. PMID: 15699051 Free article.

7

Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway.

Saydam O, Shen Y, Würdinger T, Senol O, Boke E, James MF, Tannous BA, Stemmer-Rachamimov AO, Yi M, Stephens RM, Fraefel C, Gusella JF, Krichevsky AM, Breakefield XO. Saydam O, et al. Among authors: james mf. Mol Cell Biol. 2009 Nov;29(21):5923-40. doi: 10.1128/MCB.00332-09. Epub 2009 Aug 24. Mol Cell Biol. 2009. PMID: 19703993 Free PMC article.

8

A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas.

Beauchamp RL, James MF, DeSouza PA, Wagh V, Zhao WN, Jordan JT, Stemmer-Rachamimov A, Plotkin SR, Gusella JF, Haggarty SJ, Ramesh V. Beauchamp RL, et al. Among authors: james mf. Oncotarget. 2015 Jul 10;6(19):16981-97. doi: 10.18632/oncotarget.4858. Oncotarget. 2015. PMID: 26219339 Free PMC article.

9

Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency.

Li L, Walsh RM, Wagh V, James MF, Beauchamp RL, Chang YS, Gusella JF, Hochedlinger K, Ramesh V. Li L, et al. Among authors: james mf. PLoS One. 2015 Oct 7;10(10):e0140192. doi: 10.1371/journal.pone.0140192. eCollection 2015. PLoS One. 2015. PMID: 26445504 Free PMC article.

10

A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.

Nigim F, Esaki S, Hood M, Lelic N, James MF, Ramesh V, Stemmer-Rachamimov A, Cahill DP, Brastianos PK, Rabkin SD, Martuza RL, Wakimoto H. Nigim F, et al. Among authors: james mf. Neuro Oncol. 2016 Sep;18(9):1278-87. doi: 10.1093/neuonc/now031. Epub 2016 Mar 6. Neuro Oncol. 2016. PMID: 26951380 Free PMC article.

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