Gorczynski MJ - Search Results

1

Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta.

Gorczynski MJ, Grembecka J, Zhou Y, Kong Y, Roudaia L, Douvas MG, Newman M, Bielnicka I, Baber G, Corpora T, Shi J, Sridharan M, Lilien R, Donald BR, Speck NA, Brown ML, Bushweller JH. Gorczynski MJ, et al. Chem Biol. 2007 Oct;14(10):1186-97. doi: 10.1016/j.chembiol.2007.09.006. Chem Biol. 2007. PMID: 17961830

2

Synthesis and evaluation of substituted 4-aryloxy- and 4-arylsulfanyl-phenyl-2-aminothiazoles as inhibitors of human breast cancer cell proliferation.

Gorczynski MJ, Leal RM, Mooberry SL, Bushweller JH, Brown ML. Gorczynski MJ, et al. Bioorg Med Chem. 2004 Mar 1;12(5):1029-36. doi: 10.1016/j.bmc.2003.12.003. Bioorg Med Chem. 2004. PMID: 14980616

3

Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by nitroalkene fatty acids: importance of nitration position and degree of unsaturation.

Gorczynski MJ, Smitherman PK, Akiyama TE, Wood HB, Berger JP, King SB, Morrow CS. Gorczynski MJ, et al. J Med Chem. 2009 Aug 13;52(15):4631-9. doi: 10.1021/jm900326c. J Med Chem. 2009. PMID: 19719236 Free PMC article.

4

Evaluation of nitroalkenes as nitric oxide donors.

Gorczynski MJ, Huang J, Lee H, King SB. Gorczynski MJ, et al. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2013-7. doi: 10.1016/j.bmcl.2007.01.016. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17270440

5

Regio- and stereospecific syntheses and nitric oxide donor properties of (E)-9- and (E)-10-nitrooctadec-9-enoic acids.

Gorczynski MJ, Huang J, King SB. Gorczynski MJ, et al. Org Lett. 2006 May 25;8(11):2305-8. doi: 10.1021/ol060548w. Org Lett. 2006. PMID: 16706512 Free PMC article.

6

Allylic nitro compounds as nitrite donors.

Chakrapani H, Gorczynski MJ, King SB. Chakrapani H, et al. Among authors: gorczynski mj. J Am Chem Soc. 2006 Dec 20;128(50):16332-7. doi: 10.1021/ja066011v. J Am Chem Soc. 2006. PMID: 17165788 Free PMC article.

7

Differential potencies of naturally occurring regioisomers of nitrolinoleic acid in PPARgamma activation.

Alexander RL, Wright MW, Gorczynski MJ, Smitherman PK, Akiyama TE, Wood HB, Berger JP, King SB, Morrow CS. Alexander RL, et al. Among authors: gorczynski mj. Biochemistry. 2009 Jan 20;48(2):492-8. doi: 10.1021/bi8016747. Biochemistry. 2009. PMID: 19105608 Free PMC article.

8

Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma.

Bates DJ, Lively MO, Gorczynski MJ, King SB, Townsend AJ, Morrow CS. Bates DJ, et al. Among authors: gorczynski mj. Biochemistry. 2009 May 19;48(19):4159-69. doi: 10.1021/bi900224c. Biochemistry. 2009. PMID: 19358561 Free PMC article.

9

Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic Response.

Vasilyeva A, Clodfelter JE, Gorczynski MJ, Gerardi AR, King SB, Salsbury F, Scarpinato KD. Vasilyeva A, et al. Among authors: gorczynski mj. J Nucleic Acids. 2010 Sep 13;2010:162018. doi: 10.4061/2010/162018. J Nucleic Acids. 2010. PMID: 20936178 Free PMC article.

10

Nitroxide derivatives of non-steroidal anti-inflammatory drugs exert anti-inflammatory and superoxide dismutase scavenging properties in A459 cells.

Flores-Santana W, Moody T, Chen W, Gorczynski MJ, Shoman ME, Velázquez C, Thetford A, Mitchell JB, Cherukuri MK, King SB, Wink DA. Flores-Santana W, et al. Among authors: gorczynski mj. Br J Pharmacol. 2012 Feb;165(4b):1058-67. doi: 10.1111/j.1476-5381.2011.01527.x. Br J Pharmacol. 2012. PMID: 21658022 Free PMC article.

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