Chan DC - Search Results

1

Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot-Marie-Tooth type 2A.

Detmer SA, Vande Velde C, Cleveland DW, Chan DC. Detmer SA, et al. Among authors: chan dc. Hum Mol Genet. 2008 Feb 1;17(3):367-75. doi: 10.1093/hmg/ddm314. Epub 2007 Oct 24. Hum Mol Genet. 2008. PMID: 17959936

2

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.

Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC. Chen H, et al. Among authors: chan dc. J Cell Biol. 2003 Jan 20;160(2):189-200. doi: 10.1083/jcb.200211046. Epub 2003 Jan 13. J Cell Biol. 2003. PMID: 12527753 Free PMC article.

3

Structural basis of mitochondrial tethering by mitofusin complexes.

Koshiba T, Detmer SA, Kaiser JT, Chen H, McCaffery JM, Chan DC. Koshiba T, et al. Among authors: chan dc. Science. 2004 Aug 6;305(5685):858-62. doi: 10.1126/science.1099793. Science. 2004. PMID: 15297672

4

Emerging functions of mammalian mitochondrial fusion and fission.

Chen H, Chan DC. Chen H, et al. Among authors: chan dc. Hum Mol Genet. 2005 Oct 15;14 Spec No. 2:R283-9. doi: 10.1093/hmg/ddi270. Hum Mol Genet. 2005. PMID: 16244327 Review.

5

Molecular mechanism of mitochondrial membrane fusion.

Griffin EE, Detmer SA, Chan DC. Griffin EE, et al. Among authors: chan dc. Biochim Biophys Acta. 2006 May-Jun;1763(5-6):482-9. doi: 10.1016/j.bbamcr.2006.02.003. Epub 2006 Mar 9. Biochim Biophys Acta. 2006. PMID: 16571363 Free article. Review.

6

Critical dependence of neurons on mitochondrial dynamics.

Chen H, Chan DC. Chen H, et al. Among authors: chan dc. Curr Opin Cell Biol. 2006 Aug;18(4):453-9. doi: 10.1016/j.ceb.2006.06.004. Epub 2006 Jun 14. Curr Opin Cell Biol. 2006. PMID: 16781135 Review.

7

Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations.

Detmer SA, Chan DC. Detmer SA, et al. Among authors: chan dc. J Cell Biol. 2007 Feb 12;176(4):405-14. doi: 10.1083/jcb.200611080. J Cell Biol. 2007. PMID: 17296794 Free PMC article.

8

Mitochondrial fusion protects against neurodegeneration in the cerebellum.

Chen H, McCaffery JM, Chan DC. Chen H, et al. Among authors: chan dc. Cell. 2007 Aug 10;130(3):548-62. doi: 10.1016/j.cell.2007.06.026. Cell. 2007. PMID: 17693261 Free article.

9

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

Song Z, Chen H, Fiket M, Alexander C, Chan DC. Song Z, et al. Among authors: chan dc. J Cell Biol. 2007 Aug 27;178(5):749-55. doi: 10.1083/jcb.200704110. Epub 2007 Aug 20. J Cell Biol. 2007. PMID: 17709429 Free PMC article.

10

Functions and dysfunctions of mitochondrial dynamics.

Detmer SA, Chan DC. Detmer SA, et al. Among authors: chan dc. Nat Rev Mol Cell Biol. 2007 Nov;8(11):870-9. doi: 10.1038/nrm2275. Nat Rev Mol Cell Biol. 2007. PMID: 17928812 Review.

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